Cubosomes: the next generation of smart lipid nanoparticles?

HMG Barriga, MN Holme… - Angewandte Chemie …, 2019 - Wiley Online Library
Cubosomes are highly stable nanoparticles formed from the lipid cubic phase and stabilized
by a polymer based outer corona. Bicontinuous lipid cubic phases consist of a single lipid …

Non-lamellar lyotropic liquid crystalline lipid nanoparticles for the next generation of nanomedicine

J Zhai, C Fong, N Tran, CJ Drummond - ACS nano, 2019 - ACS Publications
Nonlamellar lyotropic liquid crystalline (LLC) lipid nanomaterials have emerged as a
promising class of advanced materials for the next generation of nanomedicine, comprising …

The cubosome-based nanoplatforms in cancer therapy: Seeking new paradigms for cancer theranostics

BHJ Gowda, MG Ahmed, SA Alshehri, S Wahab… - Environmental …, 2023 - Elsevier
Lyotropic liquid crystals are self-assembled, non-lamellar, and mesophase nanostructured
materials that have garnered significant attention as drug carriers. Cubosomes, a subtype of …

Composition-switchable liquid crystalline nanostructures as green formulations of curcumin and fish oil

M Rakotoarisoa, B Angelov, S Espinoza… - ACS Sustainable …, 2021 - ACS Publications
Green compositions and processes for fabrication of dual-and multiloaded nanocarriers with
an antioxidant functionality and neuroprotective, cardioprotective, antiviral, and …

Cubosomes and hexosomes as versatile platforms for drug delivery

IDM Azmi, SM Moghimi, A Yaghmur - Therapeutic delivery, 2015 - Taylor & Francis
Nonlamellar liquid crystalline phases are attractive platforms for drug solubilization and
targeted delivery. The attractiveness of this formulation principle is linked to the …

Toxicity and cellular uptake of lipid nanoparticles of different structure and composition

JB Strachan, BP Dyett, Z Nasa, C Valery… - Journal of colloid and …, 2020 - Elsevier
Cubosomes form part of the next generation of lipid nanoparticle drug delivery vehicles,
enabling higher drug encapsulation efficiency, particularly for lipophilic drugs, compared to …

Cubosomes stabilized by a polyphosphoester-analog of Pluronic F127 with reduced cytotoxicity

M Fornasier, S Biffi, B Bortot, P Macor, A Manhart… - Journal of colloid and …, 2020 - Elsevier
Lyotropic liquid crystalline nanoparticles with bicontinuous cubic internal nanostructure,
known as cubosomes, have been proposed as nanocarriers in various medical applications …

Vesicular approach of cubosomes, its components, preparation techniques, evaluation and their appraisal for targeting cancer cells

S Iqbal, M Zaman, MA Waqar, HS Sarwar… - Journal of Liposome …, 2024 - Taylor & Francis
Cancer has been characterized by abnormal and uncontrolled proliferation of cells. Majority
of drugs given through chemotherapy produce unwanted and adverse effects of …

Cubosome nanoparticles for enhanced delivery of mitochondria anticancer drug elesclomol and therapeutic monitoring via sub-cellular NAD (P) H multi-photon …

AR Faria, OF Silvestre, C Maibohm, RMR Adão… - Nano Research, 2019 - Springer
Elesclomol (ELC) is an anticancer drug inducing mitochondria cytotoxicity through reactive
oxygen species. Here, for the first time, we encapsulate the poorly water soluble ELC in …

Progress and challenges of lyotropic liquid crystalline nanoparticles for innovative therapies

AVP Silvestrini, BW Debiasi, FG Praça… - International Journal of …, 2022 - Elsevier
Since the late 20th century, we have witnessed a growing and substantial advance in
nanomedicine, in part due to the development of multifunctional and multimodal …