Relevant human tissue resources and laboratory models for use in endometriosis research
Endometriosis is characterized by the growth of endometrium‐like tissue outside the uterus,
most commonly on the pelvic peritoneum and ovaries. Although it may be asymptomatic in …
most commonly on the pelvic peritoneum and ovaries. Although it may be asymptomatic in …
Nerve fibers and endometriotic lesions: partners in crime in inflicting pains in women with endometriosis
D Yan, X Liu, SW Guo - European Journal of Obstetrics & Gynecology and …, 2017 - Elsevier
One of major objectives in treating endometriosis is to alleviate pain since dysmenorrhea
and other types of pain top the list of complaints from women with endometriosis who seek …
and other types of pain top the list of complaints from women with endometriosis who seek …
Effects of inhibiting the PI3K/Akt/mTOR signaling pathway on the pain of sciatic endometriosis in a rat model
Y Liu, X Qin, X Lu, J Jiang - Canadian journal of physiology and …, 2019 - cdnsciencepub.com
This study investigated the relationship between the pain of sciatic endometriosis and the
phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin …
phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin …
Preclinical models of endometriosis and interstitial cystitis/bladder pain syndrome: an Innovative Medicines Initiative-PainCare initiative to improve their value for …
P Nunez-Badinez, B De Leo, A Laux-Biehlmann… - Pain, 2021 - journals.lww.com
Endometriosis (ENDO) and interstitial cystitis/bladder pain syndrome (IC/BPS) are chronic
pain conditions for which better treatments are urgently needed. Development of new …
pain conditions for which better treatments are urgently needed. Development of new …
Fractalkine/CX3CR1 contributes to endometriosis-induced neuropathic pain and mechanical hypersensitivity in rats
Z Liu, S Chen, C Qiu, Y Sun, W Li, J Jiang… - Frontiers in cellular …, 2018 - frontiersin.org
Pain is the most severe and common symptom of endometriosis. Its underlying pathogenetic
mechanism is poorly understood. Nerve sensitization is a particular research challenge, due …
mechanism is poorly understood. Nerve sensitization is a particular research challenge, due …
Perineural invasion in endometriotic lesions contributes to endometriosis-associated pain
Y Liang, D Liu, F Yang, W Pan, F Zeng, J Wu… - Journal of Pain …, 2018 - Taylor & Francis
Purpose Recent studies have shown that abnormal distribution of pelvic nerves contributes
to endometriosis-associated pain. However, the relationship between neurogenesis and …
to endometriosis-associated pain. However, the relationship between neurogenesis and …
Anti-nociceptive and anti-inflammatory effects of sulforaphane on sciatic endometriosis in a rat model
Y Liu, Z Zhang, X Lu, J Meng, X Qin, J Jiang - Neuroscience Letters, 2020 - Elsevier
Endometriosis of sciatic nerve is a common gynecological disease. Here we aimed to study
the anti-inflammatory and anti-nociceptive role of sulforaphane on sciatic nerve …
the anti-inflammatory and anti-nociceptive role of sulforaphane on sciatic nerve …
Identification of early symptoms of endometriosis through the analysis of online social networks: A social media study
M Fruchart, F El Idrissi, A Lamer, K Belarbi… - Digital …, 2023 - journals.sagepub.com
Objective Endometriosis is a complex full-body inflammation disease with an average time
to diagnosis of 7–10 years. Social networks give opportunity to patient to openly discuss …
to diagnosis of 7–10 years. Social networks give opportunity to patient to openly discuss …
Endometriosis-associated pain–do preclinical rodent models provide a good platform for translation?
E Greaves, M Rosser, PTK Saunders - Animal Models for Endometriosis …, 2020 - Springer
Pelvic pain is a common symptom of endometriosis. Our understanding of its etiology
remains incomplete and medical management is limited by poor translation from preclinical …
remains incomplete and medical management is limited by poor translation from preclinical …
Behavioural and neural responses to aversive visceral stimuli in women with primary dysmenorrhoea
B Böttcher, ER Gizewski, C Siedentopf… - … Journal of Pain, 2019 - Wiley Online Library
Background Chronic pelvic pain, in particular dysmenorrhoea, is a significant yet unresolved
healthcare problem in gynaecology. As interoceptive sensitivity and underlying neural …
healthcare problem in gynaecology. As interoceptive sensitivity and underlying neural …