Over 35 years ago the cell biology community was introduced to connexins as the subunit
employed to assemble semicrystalline clusters of intercellular channels that had been well …

Genetic variants in gene-encoding proteins involved in cell–cell connecting structures, such
as desmosomes and gap junctions, may cause a skin and/or cardiac phenotype, of which …

Epidermal keratinocytes are enriched with at least nine connexins that are key regulators of
epidermal homeostasis. The role of Cx30. 3 in keratinocytes and epidermal health became …

Erythrokeratodermia variabilis et progressiva (EKVP) is a rare hereditary skin disorder
characterized by hyperkeratotic plaques and erythematous patches that progressively …

Connexins are channel-forming proteins that function to facilitate gap junctional intercellular
communication. Here, we use dual cell voltage clamp and dye transfer studies to …

The 21-member connexin family found in humans is the building block of both single-
membrane spanning channels (hemichannels) and double-membrane spanning …

Phosphorylation of connexin 43 (Cx43) is an important regulatory mechanism of gap
junction (GJ) function. Cx43 is modified by several kinases on over 15 sites within its~ 140 …