[HTML][HTML] The dualistic model of ovarian carcinogenesis: revisited, revised, and expanded

RJ Kurman, IM Shih - The American journal of pathology, 2016 - Elsevier
Since our proposal of a dualistic model of epithelial ovarian carcinogenesis more than a
decade ago, a large number of molecular and histopathologic studies were published that …

Ovarian borderline tumors in the 2014 WHO classification: evolving concepts and diagnostic criteria

S Hauptmann, K Friedrich, R Redline, S Avril - Virchows archiv, 2017 - Springer
Borderline ovarian tumors (BOT) are uncommon but not rare epithelial ovarian neoplasms,
intermediate between benign and malignant categories. Since BOT were first identified> 40 …

The evolution of ovarian carcinoma subclassification

M Köbel, EY Kang - Cancers, 2022 - mdpi.com
Simple Summary Historically, cancers presenting with their main tumor mass in the ovary
have been classified as ovarian carcinomas (a concise term for epithelial ovarian cancer) …

Ovarian cancers: genetic abnormalities, tumor heterogeneity and progression, clonal evolution and cancer stem cells

U Testa, E Petrucci, L Pasquini, G Castelli, E Pelosi - Medicines, 2018 - mdpi.com
Four main histological subtypes of ovarian cancer exist: serous (the most frequent),
endometrioid, mucinous and clear cell; in each subtype, low and high grade. The large …

[HTML][HTML] Multiclonal tumor origin: Evidence and implications

BL Parsons - Mutation research/reviews in mutation research, 2018 - Elsevier
An accurate understanding of the clonal origins of tumors is critical for designing effective
strategies to treat or prevent cancer and for guiding the field of cancer risk assessment. The …

TNF-α expression, risk factors, and inflammatory exposures in ovarian cancer: evidence for an inflammatory pathway of ovarian carcinogenesis?

M Gupta, A Babic, AH Beck, K Terry - Human pathology, 2016 - Elsevier
Inflammatory cytokines, like tumor necrosis factor–alpha (TNF-α) and interleukin-6 (IL-6), are
elevated in ovarian cancer. Differences in cytokine expression by histologic subytpe or …

Two types of primary mucinous ovarian tumors can be distinguished based on their origin

M Simons, F Simmer, J Bulten, MJ Ligtenberg… - Modern …, 2020 - nature.com
The origin of primary mucinous ovarian tumors is unknown. We explore the hypothesis that
they originate from either Brenner tumors or teratomas and examine differences between the …

When is “type I” ovarian cancer not “type I”? Indications of an out-dated dichotomy

C Salazar, IG Campbell, KL Gorringe - Frontiers in oncology, 2018 - frontiersin.org
The dualistic classification of epithelial ovarian cancer (EOC) into “type I” and “type II” is
widely applied in the research setting; it is used as a convenient way of conceptualizing …

Brenner tumor of the ovary: a 10-year single institution experience and comprehensive review of the literature

F Alloush, HF Bahmad, B Lutz, R Poppiti, M Recine… - Medical …, 2023 - mdpi.com
Brenner tumors (BTs) are surface-epithelial stromal cell tumors that are categorized by the
World Health Organization as benign, borderline, and malignant. Due to the rarity of BTs, the …

Primary retroperitoneal carcinomas: new insights into pathogenesis and clinical management in comparison with ovarian carcinomas and carcinoma of unknown …

I Otsuka - Cancers, 2023 - mdpi.com
Simple Summary Primary retroperitoneal carcinomas are very rare tumors. Their
pathogenesis remains unknown but may be associated with that of ovarian carcinomas …