Organ‐on‐a‐chip platforms: a convergence of advanced materials, cells, and microscale technologies
S Ahadian, R Civitarese, D Bannerman… - Advanced …, 2018 - Wiley Online Library
Significant advances in biomaterials, stem cell biology, and microscale technologies have
enabled the fabrication of biologically relevant tissues and organs. Such tissues and organs …
enabled the fabrication of biologically relevant tissues and organs. Such tissues and organs …
Induced pluripotent stem cells: applications in regenerative medicine, disease modeling, and drug discovery
Recent progresses in the field of Induced Pluripotent Stem Cells (iPSCs) have opened up
many gateways for the research in therapeutics. iPSCs are the cells which are …
many gateways for the research in therapeutics. iPSCs are the cells which are …
An efficient nonviral method to generate integration-free human-induced pluripotent stem cells from cord blood and peripheral blood cells
K Okita, T Yamakawa, Y Matsumura, Y Sato… - Stem …, 2013 - academic.oup.com
The generation of induced pluripotent stem cells (iPSCs) provides the opportunity to use
patient-specific somatic cells, which are a valuable source for disease modeling and drug …
patient-specific somatic cells, which are a valuable source for disease modeling and drug …
Genomic instability of iPSCs: challenges towards their clinical applications
M Yoshihara, Y Hayashizaki, Y Murakawa - Stem cell reviews and reports, 2017 - Springer
Induced pluripotent stem cells (iPSCs) are a type of pluripotent stem cells generated directly
from mature cells through the introduction of key transcription factors. iPSCs can be …
from mature cells through the introduction of key transcription factors. iPSCs can be …
Induced pluripotent stem cells: the new patient?
Worldwide increases in life expectancy have been paralleled by a greater prevalence of
chronic and age-associated disorders, particularly of the cardiovascular, neural and …
chronic and age-associated disorders, particularly of the cardiovascular, neural and …
Induced pluripotent stem cells—opportunities for disease modelling and drug discovery
M Grskovic, A Javaherian, B Strulovici… - Nature reviews Drug …, 2011 - nature.com
The ability to generate induced pluripotent stem cells (iPSCs) from patients, and an
increasingly refined capacity to differentiate these iPSCs into disease-relevant cell types …
increasingly refined capacity to differentiate these iPSCs into disease-relevant cell types …
Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome
The generation of reprogrammed induced pluripotent stem cells (iPSCs) from patients with
defined genetic disorders holds the promise of increased understanding of the aetiologies of …
defined genetic disorders holds the promise of increased understanding of the aetiologies of …
Generation of induced pluripotent stem cells from human terminally differentiated circulating T cells
The direct reprogramming of somatic cells to produce induced pluripotent stem cells (iPSCs)
is a prominent recent advance in stem cell biology (Takahashi and Yamanaka, 2006) …
is a prominent recent advance in stem cell biology (Takahashi and Yamanaka, 2006) …
The pathobiology of thrombosis, microvascular disease, and hemorrhage in the myeloproliferative neoplasms
HC Hasselbalch, M Elvers… - Blood, The Journal of the …, 2021 - ashpublications.org
Thrombotic, vascular, and bleeding complications are the most common causes of morbidity
and mortality in the Philadelphia chromosome–negative myeloproliferative neoplasms …
and mortality in the Philadelphia chromosome–negative myeloproliferative neoplasms …
Investigating human disease using stem cell models
JL Sterneckert, P Reinhardt, HR Schöler - Nature Reviews Genetics, 2014 - nature.com
Tractable and accurate disease models are essential for understanding disease
pathogenesis and for developing new therapeutics. As stem cells are capable of self …
pathogenesis and for developing new therapeutics. As stem cells are capable of self …