Innate immune response to lipooligosaccharide: pivotal regulator of the pathobiology of invasive Neisseria meningitidis infections
Infections due to Neisseria meningitidis afflict more than one million people worldwide
annually and cause death or disability in many survivors. The clinical course of invasive …
annually and cause death or disability in many survivors. The clinical course of invasive …
How the Knowledge of Interactions between Meningococcus and the Human Immune System Has Been Used to Prepare Effective Neisseria meningitidis Vaccines
In the last decades, tremendous advancement in dissecting the mechanisms of
pathogenicity of Neisseria meningitidis at a molecular level has been achieved, exploiting …
pathogenicity of Neisseria meningitidis at a molecular level has been achieved, exploiting …
Meningitis caused by Neisseria Meningitidis, Hemophilus Influenzae Type B and Streptococcus Pneumoniae during 2005–2012 in Turkey: A multicenter prospective …
M Ceyhan, N Gürler, Y Ozsurekci, M Keser… - Human vaccines & …, 2014 - Taylor & Francis
Successful vaccination policies for protection from bacterial meningitis are dependent on
determination of the etiology of bacterial meningitis. Cerebrospinal fluid (CSF) samples were …
determination of the etiology of bacterial meningitis. Cerebrospinal fluid (CSF) samples were …
A comparative evaluation of two investigational meningococcal ABCWY vaccine formulations: results of a phase 2 randomized, controlled trial
SL Block, L Szenborn, W Daly, T Jackowska… - Vaccine, 2015 - Elsevier
Background A meningococcal vaccine protective against all major disease-associated
serogroups (A, B, C, W and Y) is an unmet public health need. In this phase 2 observer …
serogroups (A, B, C, W and Y) is an unmet public health need. In this phase 2 observer …
[HTML][HTML] Targeted DNA enrichment and whole genome sequencing of Neisseria meningitidis directly from clinical specimens
Abstract In England and Wales, approximately one half of all laboratory-confirmed
meningococcal disease cases fail to yield a viable invasive isolate, primarily due to the use …
meningococcal disease cases fail to yield a viable invasive isolate, primarily due to the use …
Vaccinating Italian infants with a new multicomponent vaccine (Bexsero®) against meningococcal B disease: A cost-effectiveness analysis
ABSTRACT The European Medicines Agency has approved a multicomponent serogroup B
meningococcal vaccine (Bexsero®) for use in individuals of 2 months of age and older. A …
meningococcal vaccine (Bexsero®) for use in individuals of 2 months of age and older. A …
Evaluation of intranasal and subcutaneous route of immunization in neonatal mice using DODAB-BF as adjuvant with outer membrane vesicles of Neisseria …
FA de Oliveira Santos, N Lincopan, E De Gaspari - Immunobiology, 2018 - Elsevier
Abstract Background The Neisseria meningitidis bacterium is a Gram-negative diplococcus
that can be classified into different serogroups according to the capsular structure. Six of …
that can be classified into different serogroups according to the capsular structure. Six of …
A deeper mining on the protein composition of VA-MENGOC-BC®: An OMV-based vaccine against N. meningitidis serogroup B and C
Y Masforrol, J Gil, D Garcia, J Noda… - Human Vaccines & …, 2017 - Taylor & Francis
The protein composition of an Outer Membrane Vesicle (OMV) preparation that constitutes
the active pharmaceutical ingredient of VA-MENGOC-BC®, an effective vaccine against …
the active pharmaceutical ingredient of VA-MENGOC-BC®, an effective vaccine against …
[HTML][HTML] Harnessing Bacterial Extracellular Vesicle Immune Effects for Cancer Therapy
There are a growing number of studies linking the composition of the human microbiome to
disease states and treatment responses, especially in the context of cancer. This has raised …
disease states and treatment responses, especially in the context of cancer. This has raised …
Why the anti-meningococcal B vaccination during adolescence should be implemented in Italy: an overview of available evidence
Although meningococcal disease has a low incidence in Italy, it is a public health concern
owing to its high lethality rate and high frequency of transitory and/or permanent sequelae …
owing to its high lethality rate and high frequency of transitory and/or permanent sequelae …