Risk factors for periodontal disease

RJ Genco, WS Borgnakke - Periodontology 2000, 2013 - Wiley Online Library
Risk factors play an important role in an individual's response to periodontal infection.
Identification of these risk factors helps to target patients for prevention and treatment, with …

Cytokine profile in chronic periodontitis patients with and without obesity: a systematic review and meta‐analysis

Z Akram, T Abduljabbar, MI Abu Hassan… - Disease …, 2016 - Wiley Online Library
To investigate the cytokine profile as biomarkers in the gingival crevicular fluid (GCF) of
chronic periodontitis (CP) patients with and without obesity, MEDLINE/PubMed, EMBASE …

Osteocyte-derived exosomes induced by mechanical strain promote human periodontal ligament stem cell proliferation and osteogenic differentiation via the miR …

P Lv, P Gao, G Tian, Y Yang, F Mo, Z Wang… - Stem cell research & …, 2020 - Springer
Background The oral cavity is a complex environment in which periodontal tissue is
constantly stimulated by external microorganisms and mechanical forces. Proper …

MicroRNAs and their target genes in gingival tissues

C Stoecklin-Wasmer, P Guarnieri… - Journal of dental …, 2012 - journals.sagepub.com
To gain insights into the in vivo function of miRNAs in the context of periodontitis, we
examined the occurrence of miRNAs in healthy and diseased gingival tissues and validated …

MicroRNAs in salivary exosome as potential biomarkers of aging

T Machida, T Tomofuji, D Ekuni, T Maruyama… - International journal of …, 2015 - mdpi.com
The aim of this study was to examine whether salivary exosomal miRNAs could be identified
as aging biomarkers. Fifteen young healthy volunteers (median age, 21.0 years) and 13 old …

Plasma-and saliva exosome profile reveals a distinct MicroRNA signature in chronic periodontitis

NNS Nik Mohamed Kamal, RAR Awang… - Frontiers in …, 2020 - frontiersin.org
Chronic periodontitis (CP) is an oral cavity disease arising from chronic inflammation of the
periodontal tissues. Exosomes are lipid vesicles that are enriched in specific microRNAs …

MicroRNAs and immunity in periodontal health and disease

X Luan, X Zhou, A Naqvi, M Francis, D Foyle… - International Journal of …, 2018 - nature.com
MicroRNAs (miRNAs) are critical regulators of the host immune and inflammatory response
against bacterial pathogens. In the present review, we discuss target genes, target gene …

Does obesity influence the subgingival microbiota composition in periodontal health and disease?

SS Maciel, M Feres, TED Gonçalves… - Journal of clinical …, 2016 - Wiley Online Library
Aim To evaluate whether obesity affects the subgingival microbial composition of patients
with periodontal health or chronic periodontitis (CP). Materials and Methods Based on …

MicroRNA-142-3p inhibits chondrocyte apoptosis and inflammation in osteoarthritis by targeting HMGB1

X Wang, Y Guo, C Wang, H Yu, X Yu, H Yu - Inflammation, 2016 - Springer
Osteoarthritis (OA) is a degenerative joint disease characterized by articular cartilage
degradation and joint inflammation in which microRNAs are significantly involved. Previous …

Osteoclastogenesis in periodontal diseases: Possible mediators and mechanisms

MS AlQranei, MA Chellaiah - Journal of oral biosciences, 2020 - Elsevier
Background Periodontitis is the inflammation of the tooth-supporting structures and is one of
the most common diseases of the oral cavity. The outcome of periodontal infections is tooth …