Strains of bacteria resistant to antibiotics, particularly those that are multiresistant, are an
increasing major health care problem around the world. It is now abundantly clear that both …

The IS 6 family of bacterial and archaeal insertion sequences, first identified in the early
1980s, has proved to be instrumental in the rearrangement and spread of multiple antibiotic …

It is well established that plasmids play an important role in the dissemination of
antimicrobial resistance (AMR) genes; however, little is known about the role of the …

ABSTRACT The IS 26 transposase, Tnp26, catalyzes IS 26 movement to a new site and
deletion or inversion of adjacent DNA via a replicative route. The intramolecular deletion …

A phenotype of Escherichia coli and Klebsiella pneumoniae, resistant to piperacillin/
tazobactam (TZP) but susceptible to carbapenems and 3rd generation cephalosporins, has …

Horizontal gene transfer (HGT) and gene duplication are often considered as separate
mechanisms driving the evolution of new functions. However, the mobile genetic elements …

The Australian silver gull is an urban-adapted species that frequents anthropogenic waste
sites. The enterobacterial flora of synanthropic birds often carries antibiotic resistance …

Carbapenem and colistin are the last-resort antibiotics used for treating multidrug-resistant
Gram-negative pathogens. Here, we report, for the first time, co-transfer of resistance to both …

Antibiotic resistance genes are often found in structures bounded by copies of IS26,
IS257/IS431 or IS1216 that resemble compound (or composite) transposons. However …

In Gram-negative bacteria, the insertion sequence IS 26 is highly active in disseminating
antibiotic resistance genes. IS 26 can recruit a gene or group of genes into the mobile gene …