Neuroglobin and cytoglobin are two recent additions to the family of heme-containing
respiratory proteins of man and other vertebrates. Here, we review the present state of …

For a long time, haemoglobin and myoglobin had been assumed to represent the only
globin types of vertebrates. In 2000, however, we discovered a third globin type by mining …

The precise cause of neuronal death in Huntington's disease (HD) is unknown. Although no
single specific protein-protein interaction of mutant huntingtin has emerged as the …

Neuroglobin (Ngb) is a globin expressed in the nervous system of humans and other
organisms that is involved in the protection of the brain from ischemic damage. Despite …

Neuroglobin, recently discovered in the brain and in the retina of vertebrates, belongs to the
class of hexacoordinate globins, in which the distal histidine coordinates the iron center in …

Dexmedetomidine (DEX) is a highly selective α2 receptor agonist that is routinely used in
the clinic for sedation and anesthesia. Recently, an increasing number of studies have …

In 2000, the third member of the globin family was discovered in human and mouse brain
and named neuroglobin (Ngb). Ngb is a monomeric 3/3 globin structurally similar to …

The heme prosthetic group in hemoglobins is most often attached to the globin through
coordination of either one or two histidine side chains. Those proteins with one histidine …

Neuroglobin (Ngb) is a newly discovered vertebrate heme protein that is expressed in the
brain and can reversibly bind oxygen. It has been reported that Ngb expression levels …

The subterranean mole rat Spalax is an excellent model for studying adaptation of a
mammal toward chronic environmental hypoxia. Neuroglobin (Ngb) and cytoglobin (Cygb) …