Why is iron deficiency/anemia linked to Alzheimer's disease and its comorbidities, and how is it prevented?
K Fehsel - Biomedicines, 2023 - mdpi.com
Impaired iron metabolism has been increasingly observed in many diseases, but a deeper,
mechanistic understanding of the cellular impact of altered iron metabolism is still lacking. In …
mechanistic understanding of the cellular impact of altered iron metabolism is still lacking. In …
Progress in the treatment of high altitude cerebral edema: Targeting REDOX homeostasis
Y Li, C Li, T Luo, T Yue, W Xiao, L Yang… - Journal of …, 2023 - Taylor & Francis
With the increasing of altitude activities from low-altitude people, the study of high altitude
cerebral edema (HACE) has been revived. HACE is a severe acute mountain sickness …
cerebral edema (HACE) has been revived. HACE is a severe acute mountain sickness …
Occlusion preconditioned mice are resilient to hypobaric hypoxia-induced myocarditis and arrhythmias due to enhanced immunomodulation, metabolic homeostasis …
Background Sea-level residents experience altitude sickness when they hike or visit
altitudes above~ 2,500 m due to the hypobaric hypoxia (HH) conditions at such places. HH …
altitudes above~ 2,500 m due to the hypobaric hypoxia (HH) conditions at such places. HH …
Exogenous H2S targeting PI3K/AKT/mTOR pathway alleviates chronic intermittent hypoxia-induced myocardial damage through inhibiting oxidative stress and …
XB Zheng, C Wang, M Zhang, BQ Yao, HY Wu… - Sleep and …, 2025 - Springer
Aims Hydrogen sulfide (H 2 S) is a novel gas signaling molecule that has been researched
in several physiological and pathological conditions, indicating that strategies targeting H 2 …
in several physiological and pathological conditions, indicating that strategies targeting H 2 …
Recent advances in predicting acute mountain sickness: from multidimensional cohort studies to cutting-edge model applications
B Wang, S Chen, J Song, D Huang, G Xiao - Frontiers in Physiology, 2024 - frontiersin.org
High-altitude illnesses, encompassing a spectrum of health threats including Acute
Mountain Sickness (AMS), pose significant challenges to individuals exposed to high …
Mountain Sickness (AMS), pose significant challenges to individuals exposed to high …
SIRT1 regulates mitochondrial fission to alleviate high altitude hypoxia inducedcardiac dysfunction in rats via the PGC-1α-DRP1/FIS1/MFF pathway
H Xu, X Song, X Zhang, G Wang, X Cheng, L Zhang… - Apoptosis, 2024 - Springer
High-altitude exposure has been linked to cardiac dysfunction. Silent information regulator
factor 2-related enzyme 1 (sirtuin 1, SIRT1), a nicotinamide adenine dinucleotide-dependent …
factor 2-related enzyme 1 (sirtuin 1, SIRT1), a nicotinamide adenine dinucleotide-dependent …
Reply to: Hypoxia treatment of Parkinson's disease may disrupt the circadian system
JM Janssen Daalen, MJ Meinders, IR Straatsma… - BMC neurology, 2023 - Springer
In recent years, increasing attention has been given to hypoxia-based treatment for persons
with neurodegenerative and mitochondrial disease, as reflected by the significant rise in …
with neurodegenerative and mitochondrial disease, as reflected by the significant rise in …
[HTML][HTML] The role and mechanism of PDZ binding kinase in hypobaric and hypoxic acute lung injury
L Sun, H Yue, H Fang, R Li, S Li, J Wang… - Journal of Thoracic …, 2024 - ncbi.nlm.nih.gov
Background Acute lung injury (ALI) caused by hypobaric hypoxia (HH) is frequently
observed in high-altitude areas, and it is one of the leading causes of death in high-altitude …
observed in high-altitude areas, and it is one of the leading causes of death in high-altitude …
[HTML][HTML] Activation of cannabinoid type 2 (CB2) receptors promotes the maintenance of redox homeostasis and protects against oxidative distress in the Neotropical …
SLA Fernandes, YC Gonçalves, FT Rantin… - Neotropical …, 2024 - SciELO Brasil
Recent evidence indicates significant interaction of cannabinoid receptors (CB1 and CB2)
with redox mechanisms. This study investigated the effects of the cannabinoid agonists WIN …
with redox mechanisms. This study investigated the effects of the cannabinoid agonists WIN …
The impact of high-altitude and cold environment on brain and heart damage in rats with hemorrhagic shock
J Xu, W Yu, N Li, S Li, X Wang, C Gao, FY Liu… - Brain …, 2024 - journals.lww.com
BACKGROUND: Hemorrhagic shock (HS) causes severe organ damage, worsened by high-
altitude conditions with lower oxygen and temperatures. Existing research lacks specific …
altitude conditions with lower oxygen and temperatures. Existing research lacks specific …