Recent advances in the understanding of the health benefits and molecular mechanisms associated with green tea polyphenols

L Xing, H Zhang, R Qi, R Tsao… - Journal of agricultural and …, 2019 - ACS Publications
Tea, leaf, or bud from the plant Camellia sinensis, make up some of the beverages popularly
consumed in different parts of the world as green tea, oolong tea, or black tea. More …

Machine learning approaches and their applications in drug discovery and design

S Priya, G Tripathi, DB Singh, P Jain… - Chemical Biology & …, 2022 - Wiley Online Library
This review is focused on several machine learning approaches used in chemoinformatics.
Machine learning approaches provide tools and algorithms to improve drug discovery. Many …

Identification of new drug-like compounds from millets as Xanthine oxidoreductase inhibitors for treatment of Hyperuricemia: A molecular docking and simulation study

RK Pathak, A Gupta, R Shukla, M Baunthiyal - Computational Biology and …, 2018 - Elsevier
Xanthine oxidoreductase plays an important role in formation of uric acid and its regulation
during purine catabolism. Uncontrolled expression of this enzyme is responsible for …

Green tea: Current trends and prospects in nutraceutical and pharmaceutical aspects

A Sarma, R Bania, MK Das - Journal of Herbal Medicine, 2023 - Elsevier
Introduction Tea, which originated in China, has spread to every part of the world and
become the most popular beverage, second to water. This review aims to broaden existing …

Computational approaches in drug discovery and design

RK Pathak, DB Singh, M Sagar, M Baunthiyal… - Computer-aided drug …, 2020 - Springer
Drug discovery is an expensive and complicated process. The drug must fulfill some criteria
of being nontoxic, bioavailable, and potent. In the view of evermore stringent demands about …

Introduction to basics of bioinformatics

RK Pathak, DB Singh, R Singh - Bioinformatics, 2022 - Elsevier
As we know that bioinformatics is recognized as the science of the 21st century and has
tremendous potential for decoding complex biological systems via analysis and integration …

Systems biology approaches for food and health

RK Pathak, DB Singh - Advances in agri-food biotechnology, 2020 - Springer
In recent years, systems biology has emerged as a powerful tool to understand crop plant
systems for augmenting food production and how their dietary components promote our …

In silico identification of mimicking molecule(s) triggering von Willebrand factor in human: a molecular drug target for regulating coagulation pathway

G Rana, RK Pathak, R Shukla… - Journal of Biomolecular …, 2020 - Taylor & Francis
Blood coagulation is a complex and dynamic process wherein the body activates its
emergency mechanism to stop bleeding and wound healing via the interactions of …

Investigation of the Skin Anti-photoaging Potential of Swertia chirayita Secoiridoids Through the AP-1/Matrix Metalloproteinase Pathway by Molecular Modeling

P Wongrattanakamon, P Nimmanpipug… - International Journal of …, 2019 - Springer
Secoiridoids are bioactive compounds, which are present in plants and exhibit anti-
inflammatory activity. In this work, to understand the structural basis of five secoiridoids; …

Natural products in cancer chemoprevention and chemotherapy

DB Singh, MK Gupta, RK Pathak - Front. Nat. Prod. Chem, 2020 - books.google.com
Cancer is a very fatal, challenging and complex disease. A large number of people across
the globe are suffering from various types of cancer. The bioactive substances isolated from …