Thiazole ring—A biologically active scaffold

A Petrou, M Fesatidou, A Geronikaki - Molecules, 2021 - mdpi.com
Background: Thiazole is a good pharmacophore nucleus due to its various pharmaceutical
applications. Its derivatives have a wide range of biological activities such as antioxidant …

[HTML][HTML] Novel pyridine and pyrimidine derivatives as promising anticancer agents: A review

M Albratty, HA Alhazmi - Arabian Journal of Chemistry, 2022 - Elsevier
Pyridines and pyrimidines are the class of heterocyclic nitrogenous compounds having
plethora of applications in anticancer drug development. These synthetic sources serve as …

Synthesis, characterization, and corrosion inhibition activity of new imidazo [1.2-a] pyridine chalcones

W Daoudi, M Azzouzi, O Dagdag, A El Boutaybi… - Materials Science and …, 2023 - Elsevier
In this work, two new Imidazo [1.2-a] pyridine chalcones (IMZs) namely, 1-(3-methylpyrazin-2-
yl)-3-(2-phenylimidazo [1, 2-a] pyridin-3-yl) prop-2-en-1-one (IMZ1) and 3-(2-(4 …

Chalcone: a promising bioactive scaffold in medicinal chemistry

G Rajendran, D Bhanu, B Aruchamy, P Ramani… - Pharmaceuticals, 2022 - mdpi.com
Chalcones are a class of privileged scaffolds with high medicinal significance due to the
presence of an α, β-unsaturated ketone functionality. Numerous functional modifications of …

Anticancer activity of natural and synthetic chalcones

T Constantinescu, CN Lungu - International journal of molecular sciences, 2021 - mdpi.com
Cancer is a condition caused by many mechanisms (genetic, immune, oxidation, and
inflammatory). Anticancer therapy aims to destroy or stop the growth of cancer cells …

Synthesis and Pharmacological Activities of Chalcone and Its Derivatives Bearing N-Heterocyclic Scaffolds: A Review

K Mezgebe, Y Melaku, E Mulugeta - ACS omega, 2023 - ACS Publications
The incorporation of heterocyclic moieties into the standard chemical structure with a
biologically active scaffold has become of crucial practice for the construction of …

Synthesis, in vitro evaluation and molecular docking studies of novel thiophenyl thiazolyl-pyridine hybrids as potential anticancer agents

FO Ashmawy, SM Gomha, MA Abdallah, MEA Zaki… - Molecules, 2023 - mdpi.com
Many literature reports revealed the anticancer activity of pyridine and thiazole derivatives,
especially in lung cancer. Therefore, a new series of thiazolyl pyridines linked with …

Recent Advances in the Synthesis of Imidazo[1,2‐a]pyridines: A Brief Review

J Panda, BP Raiguru, M Mishra, S Mohapatra… - …, 2022 - Wiley Online Library
This review focuses on providing comprehensive highlights of the recent synthetic pathways
of imidazo [1, 2‐a] pyridines, assisted through transition metal‐catalyzed reactions, multi …

Evaluation of the corrosion inhibition of mild steel by newly synthesized imidazo [1, 2-a] pyridine derivatives: experimental and theoretical investigation

W Daoudi, L Guo, M Azzouzi… - Journal of Adhesion …, 2023 - Taylor & Francis
In the pickling industry, corrosion can deteriorate the quality of equipment and supplies,
causing financial losses and safety threats. Therefore, it has become crucial to develop …

Anticancer effects of licochalcones: A review of the mechanisms

N Deng, M Qiao, Y Li, F Liang, J Li, Y Liu - Frontiers in Pharmacology, 2023 - frontiersin.org
Cancer is a disease with a high fatality rate representing a serious threat to human health.
Researchers have tried to identify effective anticancer drugs. Licorice is a widely used …