Biopolymer-based nano-formulations for mitigation of ocular infections: a review

D Karati, S Mukherjee, S Singh, BG Prajapati, B Basu - Polymer Bulletin, 2024 - Springer
Ocular infirmities significantly influence a person's routine process by impairing vision to the
point of blindness. Effective ocular drug administration with significant bioavailability is …

[HTML][HTML] Solubilization techniques used for poorly water-soluble drugs

B Xie, Y Liu, X Li, P Yang, W He - Acta Pharmaceutica Sinica B, 2024 - Elsevier
Currently, about 40% of approved drugs and nearly 90% of drug candidates are poorly
water-soluble drugs. Low solubility reduces the likelihood that these drugs can be effectively …

Supramolecular corrosion protection: Eco-friendly synthesis and efficacy of a β-cyclodextrin/o-phenylenediamine complex

I Eliboev, E Berdimurodov, K Yakhshinorov… - Journal of the Taiwan …, 2023 - Elsevier
Background In corrosion science, organic inhibitors were widely used to protect the metal
from corrosion. However, the greenness and effectiveness are a problem for organic …

Characterization of thymoquinone-sulfobutylether-β-cyclodextrin inclusion complex for anticancer applications

EEM Eid, AA Almaiman, SA Alshehade, W Alsalemi… - Molecules, 2023 - mdpi.com
Thymoquinone (TQ) is a quinone derived from the black seed Nigella sativa and has been
extensively studied in pharmaceutical and nutraceutical research due to its therapeutic …

[HTML][HTML] Oral Administration of Berberine Hydrochloride Based on Chitosan/Carboxymethyl-β-Cyclodextrin Hydrogel

BF Clemence, L Xiao, G Yang - Polymers, 2024 - mdpi.com
In this study, a novel oral formulation of berberine hydrochloride (BBH) hydrogel was
successfully synthesized through physical cross-linking using chitosan (CS) and …

Enhancing the anti-leukemic potential of thymoquinone/sulfobutylether-β-cyclodextrin (SBE-β-CD) inclusion complexes

EEM Eid, SA Alshehade, AA Almaiman, S Kamran… - Biomedicines, 2023 - mdpi.com
Leukemia, a condition characterized by the abnormal proliferation of blood cells, poses
significant challenges in cancer treatment. Thymoquinone (TQ), a bioactive compound …

Sulfobutyl ether cyclodextrin inclusion complexes containing tea polyphenols: Preparation, characterization, antioxidant activity, α-glucosidase inhibition, and in vitro …

N Li, B Feng, Y Bi, F Kong, Z Wang, S Tan - Journal of Molecular Structure, 2024 - Elsevier
Tea polyphenols (TP) is popular due to strong biological activity, however, the instability of
TP limits its application. In this study, inclusion complexes (TP-SBE) of TP with sulfobutyl …

Febuxostat ternary inclusion complex using SBE7-βCD in presence of a water-soluble polymer: physicochemical characterization, in vitro dissolution, and in vivo …

W Sakran, M Abdel-Hakim, MS Teiama… - Drug Delivery and …, 2024 - Springer
Febuxostat (FBX), a potent xanthine oxidase inhibitor, is widely used as a blood uric acid-
reducing agent and has recently shown a promising repurposing outcome as an anti-cancer …

[HTML][HTML] Theoretical Investigations on Free Energy of Binding Cilostazol with Different Cyclodextrins as Complex for Selective PDE3 Inhibition

M Hoelm, N Chowdhury, S Biswas, A Bagchi… - Molecules, 2024 - mdpi.com
Cilostazol is a phosphodiesterase III inhibitor characterized by poor solubility. This limitation
can be overcome by using a drug carrier capable of delivering the drug to the target site …

Inclusion complexes of nabumetone with β-cyclodextrins: Spectroscopic, spectrometric and calorimetric studies in solution

D Klarić, M Kelrajter, A Čikoš, A Budimir… - Journal of Molecular …, 2024 - Elsevier
The complexation of nabumetone (NAB) with various cyclodextrins (CDs): β-cyclodextrin (β-
CD), hydroxypropyl-β-CD (HPβCD), randomly methylated β-CD (RMβCD), and …