The condensation of 5-aminopyrazole with various bielectrophilic moieties results in the
formation of pyrazoloazines, an interesting array of fused heterocyclic systems. The …

Pyrazolo [1, 5-a] pyrimidines are the dominant motif of many drugs; for instance, zaleplon
and indiplon are sedative agents and ocinaplon was identified as an anxiolytic agent. The …

Pyrazoles have attracted great attention in organic and medicinal chemistry, due to their
proven utility as synthetic intermediates for the preparation of diverse bioactive compounds …

New I2-catalyzed multicomponent bicyclization reactions of β-ketonitriles with sulfonyl
hydrazides have been established, providing a direct and metal-free access toward …

In this paper, we have developed and introduced [Zr‐UiO‐66‐PDC‐(CH2) 4‐SO3] as a
basic alkane‐sulfonate metal‐organic framework (MOF) catalyst. This catalyst was applied …

Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that primarily affects
the joints, with the main clinical manifestations being chronic, symmetrical, and peripheral …

Mercury is considered as a highly toxic metal ion due to its lethal effects on humans and the
ecological system. The increasing level of antimicrobial resistance are threatening to the …

Condensation of enynones readily available from cheap starting material with
pyrazolamines provides easy access to fluorescent 7-(trimethylsilylethynyl) pyrazolo [1, 5-a] …

In this review, a timeline starting at the willow bark and ending in the latest discoveries of
analgesic and anti-inflammatory drugs will be discussed. Furthermore, the chemical features …

Rheumatoid arthritis (RA) is a chronic disease that seriously affects human health and
quality of life, and it is one of the main causes of labor loss and disability. Many countries …