HIV has evolved many strategies to avoid neutralizing antibody responses, particularly to
conserved regions on the external glycoprotein spikes of the virus. Nevertheless, a small …

Background Acute human immunodeficiency virus type 1 (HIV-1) infection is a major
contributor to transmission of HIV-1. An understanding of acute HIV-1 infection may be …

Background. We examined whether viral dynamics in the genital tract during the natural
history of acute human immunodeficiency virus type 1 (HIV-1) infection could explain …

During primary HIV infection the viral load in plasma increases, reaches a peak, and then
declines. Phillips has suggested that the decline is due to a limitation in the number of cells …

When antiretroviral therapy first became available, it was hypothesized that the modest
clinical benefits seen in patients with advanced disease [1] would be more pronounced in …

Objective: To determine the rate of plasma HIV-1 RNA rebound in patients stopping highly
active antiretroviral therapy (HAART) after achieving undetectable viral load. Design …

HIV dynamics studies have significantly contributed to the understanding of HIV infection
and antiviral treatment strategies. But most studies are limited to short-term viral dynamics …

Objective: To study primary HIV-1 infections (PHI) using molecular and epidemiological
approaches in order to assess correlates of transmission in this population. Methods …

Background: We address the research questions:(i) what proportion of new HIV infections is
transmitted from people who are (a) undiagnosed,(b) in primary HIV infection (PHI),(c) on …

Method Eight patients were followed from a median of 5 days from the onset of PHI illness.
Plasma HIV-1 RNA levels were measured frequently and the results were fitted to …