Increasing incidence of early-onset colorectal cancer

FA Sinicrope - New England Journal of Medicine, 2022 - Mass Medical Soc
Early-Onset Colorectal Cancer Early-onset disease (at< 50 years of age) accounts for 10%
of colorectal cancer cases, and the incidence is increasing, particularly in high-income …

Is early-onset cancer an emerging global epidemic? Current evidence and future implications

T Ugai, N Sasamoto, HY Lee, M Ando… - Nature Reviews …, 2022 - nature.com
Over the past several decades, the incidence of early-onset cancers, often defined as
cancers diagnosed in adults< 50 years of age, in the breast, colorectum, endometrium …

Characteristics of early-onset vs late-onset colorectal cancer: a review

R Collaborative, AM Zaborowski, A Abdile… - JAMA …, 2021 - jamanetwork.com
Importance The incidence of early-onset colorectal cancer (younger than 50 years) is rising
globally, the reasons for which are unclear. It appears to represent a unique disease …

Rising incidence of early-onset colorectal cancer—A call to action

N Akimoto, T Ugai, R Zhong, T Hamada… - Nature reviews Clinical …, 2021 - nature.com
The incidence of early-onset colorectal cancer (CRC), which occurs in individuals< 50 years
of age, has been increasing worldwide and particularly in high-income countries. The …

Early‐onset colorectal cancer in young individuals

G Mauri, A Sartore‐Bianchi, AG Russo… - Molecular …, 2019 - Wiley Online Library
Treatment of young adults with colorectal cancer (CRC) represents an unmet clinical need,
especially as diagnosis in this population might lead to the greatest loss of years of life …

The increasing incidence of young-onset colorectal cancer: a call to action

DJ Ahnen, SW Wade, WF Jones, R Sifri… - Mayo Clinic …, 2014 - Elsevier
Abstract In the United States, colorectal cancer (CRC) is the third most common and second
most lethal cancer. More than one-tenth of CRC cases (11% of colon cancers and 18% of …

Emerging trends in colorectal cancer: Dysregulated signaling pathways

R Ahmad, JK Singh, A Wunnava… - International …, 2021 - spandidos-publications.com
Colorectal cancer (CRC) is the third most frequently detected type of cancer, and the second
most common cause of cancer-related mortality globally. The American Cancer Society …

Advanced-stage colorectal cancer in persons younger than 50 years not associated with longer duration of symptoms or time to diagnosis

FW Chen, V Sundaram, TA Chew… - Clinical gastroenterology …, 2017 - Elsevier
Background & Aims The incidence of colorectal cancer (CRC) is increasing in the United
States among adults younger than the age of 50 years. Studies of young-onset CRC have …

The rising incidence of younger patients with colorectal cancer: questions about screening, biology, and treatment

LC Connell, JM Mota, MI Braghiroli, PM Hoff - Current treatment options in …, 2017 - Springer
Opinion statement Colorectal cancer (CRC) is the third leading cancer diagnosed globally
and an important cause of cancer-related mortality. Of interest, while we have witnessed a …

Colorectal cancer outcomes and treatment patterns in patients too young for average‐risk screening

ZM Abdelsattar, SL Wong, SE Regenbogen… - Cancer, 2016 - Wiley Online Library
BACKGROUND Although colorectal cancer (CRC) screening guidelines recommend
initiating screening at age 50 years, the percentage of cancer cases in younger patients is …