The prototypic acute-phase reactant C-reactive protein (CRP) has long been recognized as
a useful marker and gauge of inflammation. CRP also plays an important role in host …

For a long time, superoxide generation by an NADPH oxidase was considered as an oddity
only found in professional phagocytes. Over the last years, six homologs of the cytochrome …

Hydroethidine (HE; or dihydroethidium) is the most popular fluorogenic probe used for
detecting intracellular superoxide radical anion. The reaction between superoxide and HE …

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in the Western
world. Its incidence has been increasing lately in developing countries. Several lines of …

Pomegranate juice is a polyphenol-rich fruit juice with high antioxidant capacity. In limited
studies in human and murine models, pomegranate juice has been shown to exert …

Inflammatory processes are important participants in the pathophysiology of hypertension
and cardiovascular disease. The identification of the mechanisms leading to the activation of …

Nitroxides can undergo one-or two-electron reduction reactions to hydroxylamines or
oxammonium cations, respectively, which themselves are interconvertible, thereby providing …

Background: Inflammation is pivotal in all phases of atherosclerosis. Among the numerous
inflammatory biomarkers, the largest amount of published data supports a role for C-reactive …

C-reactive protein is postulated to embody an index that can reflect cardiovascular risk and
can be used to independently predict major cardiovascular events and mortality. On the …

Diabetic patients are frequently affected by coronary microvascular dysfunction (CMD), a
condition consisting of a combination of altered vasomotion and long-term structural change …