Tau protein aggregation is a defining characteristic of Alzheimer's disease (AD), leading to
the formation of neurofibrillary tangles that disrupt neural communication and ultimately …

Once considered unconventional cellular structures, membraneless organelles (MLOs),
cellular substructures involved in biological processes or pathways under physiological …

Amyloid plaques and tau tangles are the hallmark pathologic features of Alzheimer's
disease (AD). Traditionally, these changes are identified in vivo via cerebrospinal fluid (CSF) …

Accurate differential diagnosis of dementia disorders including Alzheimer disease (AD),
frontotemporal dementia (FTD), dementia with Lewy bodies (DLB), Parkinson disease …

Antibodies that can selectively remove rogue proteins in the brain are an obvious choice to
treat neurodegenerative disorders (NDs), but after decades of efforts, only two antibodies to …

Alzheimer's disease (AD) is one of the most common neurodegenerative diseases. Its
etiology and associated mechanisms are still unclear, which largely hinders the …

One standing challenge for Alzheimer's disease (AD) research is early diagnosis, which
provides a time window for early intervention. Sharmin et al recently reported a positive …

Alzheimer's disease (AD) is a complex/multifactorial brain disorder involving hundreds of
defective genes, epigenetic aberrations, cerebrovascular alterations, and environmental risk …

Dementia is a group of diseases, including Alzheimer's disease (AD), vascular dementia,
Lewy body dementia, frontotemporal dementia, Parkinson's disease dementia, metabolic …

Tau protein truncated at aspartate 421 (Asp421) is a characteristic feature of Alzheimer's
disease (AD) and other tauopathies. It is likely to have a role in their pathogenesis by …