The epigenetic state of the cell of origin defines mechanisms of leukemogenesis
Z Li, S Fierstein, M Tanaka-Yano, K Frenis, CC Chen… - Leukemia, 2024 - nature.com
Acute myeloid leukemia (AML) shows variable clinical outcome. The normal hematopoietic
cell of origin impacts the clinical behavior of AML, with AML from hematopoietic stem cells …
cell of origin impacts the clinical behavior of AML, with AML from hematopoietic stem cells …
[HTML][HTML] Mechanistic insights into the developmental origin of pediatric hematological disorders
G Camiolo, CG Mullen, K Ottersbach - Experimental Hematology, 2024 - Elsevier
Embryonic and fetal hematopoietic stem and progenitor cells differ in some key properties
from cells that are part of the adult hematopoietic system. These include higher proliferation …
from cells that are part of the adult hematopoietic system. These include higher proliferation …