Platelets are anucleate cytoplasmic fragments derived from the fragmentation of medullary
megakaryocytes. Activated platelets adhere to the damaged endothelium by means of …

When platelet numbers are low or when their function is disabled, the risk of bleeding is
high, which on the one hand indicates that in normal life vascular damage is a rather …

Microparticles (MPs) derived from platelets, monocytes, endothelial cells, red blood cells,
and granulocytes may be detected in low concentrations in normal plasma and at increased …

Hemodialysis, the most common modality of renal replacement therapy, is critically required
to remove uremic toxins from the blood of patients with end-stage kidney disease. However …

Microparticles (MP) are vesicular structures released from cells upon activation, malignant
transformation, stress, or death. MP may be derived from the plasma membrane (shed …

Objective–To review the current model describing coagulation processes, including the
critical contributions of cells. Data Sources–Original research articles, scientific reviews, and …

There is increasing research on and clinical interest in the physiological role played by
platelet microparticles (PMPs). PMPs are 0.1–1-μm fragments shed from plasma …

Sickle cell anaemia (SCA) is the consequence of abnormal haemoglobin production due to
an inherited point mutation in the β‐globin gene. The resulting haemoglobin tetramer is …

The phenomenon of multidrug resistance (MDR) in cancer is associated with the
overexpression of the ATP-binding cassette (ABC) transporter proteins, including multidrug …

Microparticles (MP) shed by platelets (PLT) during storage have procoagulant activities, but
little is known about their properties to modify inflammation or immunity. In this study, we …