Therapeutic application of anti-angiogenic nanomaterials in cancers

S Mukherjee, CR Patra - Nanoscale, 2016 - pubs.rsc.org
Angiogenesis, the formation of new blood vessels from pre-existing vasculature, plays a vital
role in physiological and pathological processes (embryonic development, wound healing …

Biomaterials for sequestration of growth factors and modulation of cell behavior

SPB Teixeira, RMA Domingues… - Advanced Functional …, 2020 - Wiley Online Library
Growth factors (GFs) are proteins secreted by cells that regulate a variety of biological
processes. Although they have long been proposed as potent therapeutic agents, their …

Insulin-like growth factor binding proteins and angiogenesis: from cancer to cardiovascular disease

T Slater, NJ Haywood, C Matthews, H Cheema… - Cytokine & growth factor …, 2019 - Elsevier
Angiogenesis is a tightly regulated activity that is vital during embryonic development and for
normal physiological repair processes and reproduction in healthy adults. Pathological …

Flavonoids from the leaves of Carya cathayensis Sarg. inhibit vascular endothelial growth factor-induced angiogenesis

SS Tian, FS Jiang, K Zhang, XX Zhu, B Jin, JJ Lu… - Fitoterapia, 2014 - Elsevier
The total flavonoids (TFs) were isolated from the leaves of Carya cathayensis Sarg.(LCC), a
well-known Chinese medicinal herb commercially cultivated in Tianmu Mountain district, a …

Injectable reactive oxygen and nitrogen species-controlling hydrogels for tissue regeneration: current status and future perspectives

P Le Thi, DL Tran, TT Hoang Thi, Y Lee… - Regenerative …, 2022 - academic.oup.com
The dual role of reactive oxygen and nitrogen species (RONS) in physiological and
pathological processes in biological systems has been widely reported. It has been recently …

SCFβ-TRCP suppresses angiogenesis and thyroid cancer cell migration by promoting ubiquitination and destruction of VEGF receptor 2

S Shaik, C Nucera, H Inuzuka, D Gao… - Journal of Experimental …, 2012 - rupress.org
The incidence of human papillary thyroid cancer (PTC) is increasing and an aggressive
subtype of this disease is resistant to treatment with vascular endothelial growth factor …

Role of silver nanoparticles (AgNPs) on the cardiovascular system

C Gonzalez, H Rosas-Hernandez, MA Ramirez-Lee… - Archives of …, 2016 - Springer
With the advent of nanotechnology, the use and applications of silver nanoparticles (AgNPs)
have increased, both in consumer products as well as in medical devices. However, little is …

Angiopoietin-1 variant reduces LPS-induced microvascular dysfunction in a murine model of sepsis

A Alfieri, JJ Watson, RA Kammerer, M Tasab, P Progias… - Critical care, 2012 - Springer
Introduction Severe sepsis is characterised by intravascular or extravascular infection with
microbial agents, systemic inflammation and microcirculatory dysfunction, leading to tissue …

Buyang Huanwu Decoction Enhances Revascularization via Akt/GSK3β/NRF2 Pathway in Diabetic Hindlimb Ischemia

XY Bao, LH Deng, ZJ Huang, AS Daror… - Oxidative Medicine …, 2021 - Wiley Online Library
Background. Peripheral arterial disease (PAD) is a typical disease of atherosclerosis, most
commonly influencing the lower extremities. In patients with PAD, revascularization remains …

CardiOmics signatures reveal therapeutically actionable targets and drugs for cardiovascular diseases

MJ Ramos-Medina, G Echeverría-Garcés… - Heliyon, 2024 - cell.com
Cardiovascular diseases are the leading cause of death worldwide, with heart failure being
a complex condition that affects millions of individuals. Single-nucleus RNA sequencing has …