Control of protein-based pattern formation via guiding cues

T Burkart, MC Wigbers, L Würthner, E Frey - Nature Reviews Physics, 2022 - nature.com
Proteins control many vital functions in living cells, such as cell growth and cell division.
Reliable coordination of these functions requires the spatial and temporal organization of …

Ras assemblies and signaling at the membrane

R Nussinov, CJ Tsai, H Jang - Current opinion in structural biology, 2020 - Elsevier
Highlights•Ras and its effectors form large complexes. Ras–PI3K is at the membrane; Ras–
Raf extends via a long linker to the cytoplasm.•The membrane and its surface are highly …

Optimized biocompatible gold nanotriangles with nir absorption for photothermal applications

CM Otero, GB Simal, MF Scocozza… - ACS Applied Nano …, 2022 - ACS Publications
Gold nanotriangles (Au NTs) present singular plasmonic properties that are particularly
attractive for photothermal applications. However, most syntheses rely on the use of …

[HTML][HTML] Myomics: myosin VI structural and functional plasticity

E Magistrati, S Polo - Current Opinion in Structural Biology, 2021 - Elsevier
Highlights•Myosin VI structural conformation dictates its interactome.•Alternative splicing
generates isoforms with specialized functions.•Coordination and competition are at the basis …

Non-muscle myosin II drives critical steps of nematocyst morphogenesis

N Garg, UK Štibler, B Eismann, M Mercker… - Iscience, 2023 - cell.com
Nematocysts are generated by secretion of proteins into a post-Golgi compartment. They
consist of a capsule that elongates into a long tube, which is coiled inside the capsule matrix …

Dimensionality reduction in bulk-boundary reaction-diffusion systems

T Burkart, BJ Müller, E Frey - Physical Review E, 2024 - APS
Intracellular protein patterns regulate many vital cellular functions, such as the processing of
spatiotemporal information or the control of shape deformations. To do so, pattern-forming …

Geometry-induced patterns through mechanochemical coupling

L Würthner, A Goychuk, E Frey - Physical Review E, 2023 - APS
Intracellular protein patterns regulate a variety of vital cellular processes such as cell
division and motility, which often involve dynamic cell-shape changes. These changes in …

[图书][B] Mutant Huntingtin Impairs the Recruitment and Activation of Motor Proteins to BDNF-Endosomes

BA Turkalj - 2023 - search.proquest.com
Huntington's Disease (HD) is a fatal disorder characterized by polyglutamine expansion of
lengths> 35Q at the N-terminus of the huntingtin gene (HTT). In HD increasing repeat length …

Modeling the interplay of mechanics and self-assembly in the actin cytoskeleton

JA Grewe - 2020 - archiv.ub.uni-heidelberg.de
Many cellular processes such as cell migration or division require a trade-off between
structural integrity and dynamic reorganization of the load-bearing elements. The actin …

A computational model for the cooperative binding and self-organization of Myosin-VI in membrane reshaping

P Blanco Dorca - 2020 - upcommons.upc.edu
The dynamic membrane reshaping processes are vital for the cells to preform its activity
normally. They are involved in a myriad of cellular pathways and can be preformed by …