MR-guided radiotherapy for prostate cancer

BR Tocco, AU Kishan, TM Ma, LGW Kerkmeijer… - Frontiers in …, 2020 - frontiersin.org
External beam radiotherapy remains the primary treatment modality for localized prostate
cancer. The radiobiology of prostate carcinoma lends itself to hypofractionation, with recent …

Magnetic resonance imaging–guided vs computed tomography–guided stereotactic body radiotherapy for prostate cancer: the MIRAGE randomized clinical trial

AU Kishan, TM Ma, JM Lamb, M Casado… - JAMA …, 2023 - jamanetwork.com
Importance Magnetic resonance imaging (MRI) guidance offers multiple theoretical
advantages in the context of stereotactic body radiotherapy (SBRT) for prostate cancer …

MR-guided hypofractionated radiotherapy: current emerging data and promising perspectives for localized prostate cancer

F Cuccia, S Corradini, R Mazzola, L Spiazzi, M Rigo… - Cancers, 2021 - mdpi.com
Simple Summary The biological features of prostate cancer as a tumor with a low alpha beta
ratio have led clinicians to consider the use of higher doses per fraction, thus gaining an …

Magnetic resonance imaging-guided stereotactic body radiotherapy for prostate cancer (mirage): a phase iii randomized trial

TM Ma, JM Lamb, M Casado, X Wang, TV Basehart… - BMC cancer, 2021 - Springer
Background Stereotactic body radiotherapy (SBRT) is becoming increasingly used in
treating localized prostate cancer (PCa), with evidence showing similar toxicity and efficacy …

ALKBH5-modified HMGB1-STING activation contributes to radiation induced liver disease via innate immune response

G Chen, Q Zhao, B Yuan, B Wang, Y Zhang, Z Li… - International Journal of …, 2021 - Elsevier
Purpose Radiation therapy, which is vital for the treatment of primary liver cancer, comes
with unavoidable liver injury, which limits its implementation. N6-methyladenosine (m6A) …

Dosimetric impact of interfraction prostate and seminal vesicle volume changes and rotation: A post-hoc analysis of a phase III randomized trial of MRI-guided versus …

TM Ma, J Neylon, M Casado, S Sharma… - Radiotherapy and …, 2022 - Elsevier
Background and purpose Interfraction volumetric changes/rotations in the prostate and
proximal seminal vesicles (SVs) might compromise target coverage when tight margins are …

Intrafraction prostate motion management during dose-escalated linac-based stereotactic body radiation therapy

D Panizza, V Faccenda, R Lucchini, MC Daniotti… - Frontiers in …, 2022 - frontiersin.org
Background Extreme hypofractionation requires tight planning margins, high dose gradients,
and strict adherence to planning criteria in terms of patient positioning and organ motion …

[HTML][HTML] Single-fraction prostate stereotactic body radiotherapy: Dose reconstruction with electromagnetic intrafraction motion tracking

M Jaccard, S Ehrbar, R Miralbell, T Hagen… - Radiotherapy and …, 2021 - Elsevier
Purpose To reconstruct the dose delivered during single-fraction urethra-sparing prostate
stereotactic body radiotherapy (SBRT) accounting for intrafraction motion monitored by …

Prostate stereotactic body radiotherapy: quantifying intra-fraction motion and calculating margins using the new BIR geometric uncertainties in daily online IGRT …

JM McNeice, N Sanilkumar… - The British Journal of …, 2023 - academic.oup.com
Objectives: To measure the magnitude of intra-fraction prostate motion (IFPM) during
stereotactic radiotherapy (SBRT) delivered without intra-fraction tracking. To assess if …

Optimal planning target margin for prostate radiotherapy based on interfractional and intrafractional variability assessment during 1.5 T MRI-guided radiotherapy

J Kim, J Sung, SJ Lee, KS Cho, BH Chung… - Frontiers in …, 2023 - frontiersin.org
Introduction We analyzed daily pre-treatment-(PRE) and real-time motion monitoring-(MM)
MRI scans of patients receiving definitive prostate radiotherapy (RT) with 1.5 T MRI …