Despite the wealth of epidemiological and experimental studies indicating the protective role
of regular physical activity/exercise training against the sequels of aging and cardiovascular …

Aging is characterized by a progressive decline in cardiac function. A critical contributor to
the age-related impairment in cardiac function is the loss of cardiac myocytes through …

The combined effects of aging and regular physical exercise was investigated on the
production of reactive oxygen species (ROS), lipid peroxidation, glutathione status, and the …

Background: Apoptosis in skeletal muscle plays an important role in tissue dysfunction
disease such as muscle atrophy. Current evidence suggests that exercise trainings may …

Evidence has been accumulating that chronic inactivity leading to muscle disuse is unlikely
to be the only explanation for the peripheral muscle dysfunction of chronic obstructive …

Strenuous exercise induces oxidative stress and modification of intracellular proteins.
Exercise training, however, upregulates endogenous antioxidant defenses and heat shock …

Background. Elevated plasma levels of interleukin (IL)-6, C-reactive protein (CRP), and D-
dimer belong to the biological alterations of the “frailty syndrome,” defining increased …

Acute contractile activity of skeletal muscle initiates the activation of signaling kinases. This
promotes the phosphorylation of transcription factors, leading to enhanced DNA binding and …

Heat shock proteins (HSPs) are, in general, prosurvival molecules within the cellular
environment, and the overexpression of even just 1 family of HSPs can lead to protection …

ABSTRACT KAWADA, S., and N. ISHII. Skeletal Muscle Hypertrophy after Chronic
Restriction of Venous Blood Flow in Rats. Med. Sci. Sports Exerc., Vol. 37, No. 7, pp. 1144 …