Real-time intraoperative guidance is essential during oncological surgery for complete and
safe tumour resection. Fluorescence imaging in the near-infrared spectrum has shown …

Fluorescence imaging is an emerging technology that can provide real-time information
about the operating field during cancer surgery. Non-specific fluorescent agents, used for …

Heptamethine cyanine dyes enable deep tissue fluorescence imaging in the near infrared
(NIR) window. Small molecule conjugates of the benchmark dye ZW800‐1 have been tested …

Cyanine is a class of fluorescent dye with meritorious fluorescence properties and has
motivated numerous researchers to explore its imaging capabilities by miscellaneous …

Although antibodies are well developed and widely used in cancer therapy and diagnostic
fields, some defects remain, such as poor tissue penetration, long in vivo metabolic …

The field of targeted therapeutics has benefitted immeasurably from the development of high-
affinity antibodies. These important ligands have facilitated the development of effective …

Cancer is a public health problem and the main cause of human mortality and morbidity
worldwide. Complete removal of tumors and metastatic lymph nodes in surgery is …

Thousands of patients die each year from residual cancer that remains following
cytoreductive surgery. Use of tumor-targeted fluorescent dyes (TTFDs) to illuminate …

As a non-antibody scaffold, monobodies based on the fibronectin type III (FN3) domain
overcome antibody size and complexity while maintaining analogous binding loops …

Fundamental clinical areas such as drug delivery and regenerative medicine require
biocompatible materials as mechanically stable scaffolds or as nanoscale drug carriers …