Cyclodextrin-based host–guest supramolecular hydrogels for local drug delivery

G Fang, X Yang, S Chen, Q Wang, A Zhang… - Coordination Chemistry …, 2022 - Elsevier
Cyclodextrin (CD) is one of the most versatile substances produced by nature and can form
supramolecular hydrogels with polymers or small molecules based on non-covalent …

Electroconductive biomaterials for cardiac tissue engineering

H Esmaeili, A Patino-Guerrero, M Hasany, MO Ansari… - Acta biomaterialia, 2022 - Elsevier
Myocardial infarction (MI) is still the leading cause of mortality worldwide. The success of cell-
based therapies and tissue engineering strategies for treatment of injured myocardium have …

Advances in injectable hydrogel strategies for heart failure treatment

S He, Z Zhang, R Luo, Q Jiang, L Yang… - Advanced Healthcare …, 2023 - Wiley Online Library
Heart failure (HF) affects 60 million people worldwide and has developed into a global
public health problem surpassing cancer and urgently needs to be solved. According to the …

[HTML][HTML] Physiological implications of myocardial scar structure

WJ Richardson, SA Clarke, TA Quinn… - Comprehensive …, 2015 - ncbi.nlm.nih.gov
Once myocardium dies during a heart attack, it is replaced by scar tissue over the course of
several weeks. The size, location, composition, structure and mechanical properties of the …

Hydrogels for tissue engineering and regenerative medicine

JA Hunt, R Chen, T van Veen, N Bryan - Journal of Materials Chemistry …, 2014 - pubs.rsc.org
Injectable hydrogels have become an incredibly prolific area of research in the field of tissue
engineering and regenerative medicine, because of their high water content, mechanical …

Biotherapeutic-loaded injectable hydrogels as a synergistic strategy to support myocardial repair after myocardial infarction

Z Zheng, Y Tan, Y Li, Y Liu, G Yi, CY Yu… - Journal of Controlled …, 2021 - Elsevier
Myocardial infarction (MI) has been considered as the leading cause of cardiovascular-
related deaths worldwide. Although traditional therapeutic agents including various …

[HTML][HTML] Drug and cell delivery for cardiac regeneration

CL Hastings, ET Roche, E Ruiz-Hernandez… - Advanced drug delivery …, 2015 - Elsevier
The spectrum of ischaemic cardiomyopathy, encompassing acute myocardial infarction to
congestive heart failure is a significant clinical issue in the modern era. This group of …

Injectable hydrogel properties influence infarct expansion and extent of postinfarction left ventricular remodeling in an ovine model

JL Ifkovits, E Tous, M Minakawa… - Proceedings of the …, 2010 - National Acad Sciences
A recent trend has emerged that involves myocardial injection of biomaterials, containing
cells or acellular, following myocardial infarction (MI) to influence the remodeling response …

Injectable hydrogel therapies and their delivery strategies for treating myocardial infarction

TD Johnson, KL Christman - Expert opinion on drug delivery, 2013 - Taylor & Francis
Introduction: Heart failure following myocardial infarction (MI) impacts millions of people
each year in the US. The field of tissue engineering has developed several potential …

Hydrogel based injectable scaffolds for cardiac tissue regeneration

J Radhakrishnan, UM Krishnan, S Sethuraman - Biotechnology advances, 2014 - Elsevier
Tissue engineering promises to be an effective strategy that can overcome the lacuna
existing in the current pharmacological and interventional therapies and heart …