There has been an upsurge of interest in the adipocyte coincident with the onset of the
obesity epidemic and the realization that adipose tissue plays a major role in the regulation …

Fat distribution is closely linked to metabolic disease risk. Distribution varies with sex,
genetic background, disease state, certain drugs and hormones, development, and aging …

Adipocytes have been studied with increasing intensity as a result of the emergence of
obesity as a serious public health problem and the realization that adipose tissue serves as …

Adipose tissue is formed at stereotypic times and locations in a diverse array of organisms.
Once formed, the tissue is dynamic, responding to homeostatic and external cues and …

Expanded adipose tissue mass increases the risk for many clinical conditions including
diabetes, hypertension, coronary atherosclerotic heart disease, and some forms of cancer …

Circulating factors are typically invoked to explain bidirectional communication between the
CNS and white adipose tissue (WAT). Thus, initiation of lipolysis has been relegated …

▪ Abstract Mammalian hibernation is a temporary suspension of euthermia allowing
endotherms to undergo reversible hypothermia and generate a marked savings in energy …

During our study of the reversal of seasonal obesity in Siberian hamsters, we found an
interaction between receptors for the pineal hormone melatonin and the sympathetic …

Obesity is associated with resistance of skeletal muscle to insulin-mediated glucose uptake,
as well as resistance of different organs and tissues to other metabolic and vascular actions …

Several major developments have occurred since the last edition of Handbook of Obesity:
Clinical Applications, including new clinical trials, discoveries related to drug use, and …