Schizophrenia is a very complex syndrome involving widespread brain multi-
dysconnectivity. Schizophrenia is marked by cognitive, behavioral, and emotional …

The heterogeneity of schizophrenia has defied efforts to derive reproducible and definitive
anatomical maps of structural brain changes associated with the disorder. We aimed to map …

Wnt signaling pathways constitute a group of signal transduction pathways that direct many
physiological processes, such as development, growth, and differentiation. Dysregulation of …

G-protein-coupled receptors (GPCRs) play an integral role in the neurobiology of psychiatric
disorders. Almost all neurotransmitters involved in psychiatric disorders act through GPCRs …

In some patients with SZ, a vulnerable brain endothelium may be interacting with
environmental stressors, such as inflammation or hypoxia, converging into a more severe SZ …

Psychiatric symptoms are interrelated and found to be largely captured by a general
psychopathology factor (GPF). Although epigenetic mechanisms, such as DNA methylation …

Schizophrenia (SZ) is a multifactorial disorder characterized by volume reduction in gray
and white matter, oxidative stress, neuroinflammation, altered neurotransmission, as well as …

Although numerous susceptibility loci for depression have been identified in recent years,
their biological function and molecular mechanism remain largely unknown. By using an …

Alzheimer's disease (AD) is the most common cause of dementia, and one of the most
common health problems all over the world. However, the specific molecular mechanisms of …

Schizophrenia is a mental disorder that arises from abnormal neurodevelopment, led by
genetic and environmental factors. Several lines of evidence suggest the involvement of …