Advances in copper complexes as anticancer agents

C Santini, M Pellei, V Gandin, M Porchia… - Chemical …, 2014 - ACS Publications
Medicinal inorganic chemistry offers additional opportunities for the design of therapeutic
agents not accessible to organic compounds. 1− 3 The wide range of coordination numbers …

An overview on synthetic 2-aminothiazole-based compounds associated with four biological activities

M Farouk Elsadek, B Mohamed Ahmed… - Molecules, 2021 - mdpi.com
Amongst sulfur-and nitrogen-containing heterocyclic compounds, the 2-aminothiazole
scaffold is one of the characteristic structures in drug development as this essential …

TCM active ingredient oxoglaucine metal complexes: crystal structure, cytotoxicity, and interaction with DNA

ZF Chen, YF Shi, YC Liu, X Hong, B Geng… - Inorganic …, 2012 - ACS Publications
The alkaloid oxoglaucine (OG), which is a bioactive component from traditional Chinese
medicine (TCM), was synthesized by a two-step reaction and used as the ligand to react with …

Synthesis, characterization and molecular docking studies of highly functionalized and biologically active derivatives of 2-aminothiazole

G Kanagasabapathy, S Britto, V Anbazhagan - Journal of Molecular …, 2023 - Elsevier
Many derivatives of 2-aminothiazoles are found to have significant biological properties and
used as potential antibacterial and antifungal drugs. Therefore new synthetic methodologies …

Substituted effect on some water-soluble Mn (II) salen complexes: DNA binding, cytotoxicity, molecular docking, DFT studies and theoretical IR & UV studies

Z Asadi, Z Mandegani, M Asadi, AH Pakiari… - … Acta Part A: Molecular …, 2019 - Elsevier
Based on the importance of central metal complexes to interact with DNA, in this research
focused on synthesis of some new water soluble Mn (II) complexes 1–4 which modified …

[HTML][HTML] Characterization and acid treatment of silica and organics in evaporator blowdown wastewater arising from SAGD operations

S Rao, G Achari, B Perdicakis, AK Mehrotra - Journal of Water Process …, 2024 - Elsevier
The evaporator blowdown (EBD) wastewater from high-pressure steam generation for the
steam-assisted gravity drainage (SAGD) bitumen extraction process contains elevated …

Instigating the In Vitro Anticancer Activity of New Pyridine–Thiazole-Based Co(III), Mn(II), and Ni(II) Complexes: Synthesis, Structure, DFT, Docking, and MD …

P Bera, A Aher, P Brandao, U Debnath… - Journal of Chemical …, 2022 - ACS Publications
The perchlorate salt of (4-(4-methoxy phenyl)-2-(2-(1-pyridine-2-yl) ethylidene) hydrazinyl)
thiazole (PytH· ClO 4) and its metal perchlorate derivatives, namely,[Co (Pyt) 2] ClO4 (1),[Mn …

Novel bisthiazole ligand and its copper (II) complex with unusual seven membered ring: Synthesis, characterization, experimental and theoretical study of the effect of …

F Velluti, A Acevedo, G Serra, J Ellena, G Borthagaray… - Polyhedron, 2021 - Elsevier
In the search of antimicrobial agents a novel bisthiazole ligand containing a methylamine
linker (ethyl 2-((2-methylthiazole-4-yl) methylamino) thiazole-4-carboxylate (BTa) and its …

New BI and TRI-Thiazole copper (II) complexes in the search of new cytotoxic drugs against breast cancer cells

N Alvarez, F Velluti, F Guidali, G Serra, MG Kramer… - Inorganica Chimica …, 2020 - Elsevier
New thiazolyl derivatives (BT and TT) and their copper (II) complexes [Cu 2 Cl 2 (BT) 2](Cu-
BT) and [Cu 4 ClO 2 (TT) 2] PF 6⋅ 3.5 H 2 O (Cu-TT) were synthesized and characterized by …

Synthesis, spectroscopic characterization, analgesic, and antimicrobial activities of Co(II), Ni(II), and Cu(II) complexes of 2-[N,N-bis-(3,5-dimethyl-pyrazolyl-1- methyl) …

M Kalanithi, M Rajarajan, P Tharmaraj… - Medicinal Chemistry …, 2015 - Springer
Synthesis of new series of Cu (II), Co (II), and Ni (II) from the ligand 2-[N, N-bis-(3, 5-dimethyl-
pyrazolyl-1-methyl)] aminothiazole is described. The ligand and its complexes were …