Abstract TFF1/pS2, TFF2/SP and TFF3/ITF are soluble peptides with trefoil domain (s) and C-
terminal dimerization domain, which are conserved among human, cow, mouse and rat …

Gastric cancer is thought to result from a combination of environmental factors and the
accumulation of specific genetic alterations due to increasing genetic instability, and …

Objective To investigate the incidence of gastric cancer (GC) attributed to gastric intestinal
metaplasia (IM), and validate the Operative Link on Gastric Intestinal Metaplasia (OLGIM) for …

Gastric carcinoma (GC) is one of the most common malignancies worldwide. To better
understand the genetic basis of this disease, we performed serial analysis of gene …

Adding anti–programmed cell death protein 1 (anti–PD-1) to 5-fluorouracil (5-FU)/platinum
improves survival in some advanced gastroesophageal adenocarcinomas (GEA). To …

Hepatocyte nuclear factor‐4α (HNF4α) exists in multiple isoforms that are generated by
alternative promoter (P1 and P2) usage and splicing. Here we establish monoclonal …

Background: The age-standardized and cumulative incidence rates of gastric cancer (GCA)
are twice as high in males as in females. Methods: Based on age-group-specific (5-year age …

Previous studies of oncogene and tumor suppressor gene alterations have suggested that
differences exist in the molecular pathogenesis of the various histological types of …

The endodermal lining of the adult gastro-intestinal tract harbours stem cells that are
responsible for the day-to-day regeneration of the epithelium. Stem cells residing in the …

BACKGROUND & AIMS: Trefoil factors (TFFs) regulate mucosal repair and suppress tumor
formation in the stomach. Tff1 deficiency results in gastric cancer, whereas Tff2 deficiency …