Reviewing the advancements in malaria treatment, the emergence of triazole hybrid
compounds stands out as a groundbreaking development. Combining the advantages of …

Malaria is among one of the most devastating and deadliest parasitic disease in the world
claiming millions of lives every year around the globe. It is a mosquito-borne infectious …

In the present study, a new series of 1, 2, 3-triazole derivatives was synthesized via a click
one-pot reaction. The synthesized compounds were found to be active during molecular …

A series of new hybrids of 1, 2, 4-triazine-quinoline were designed, synthesized and
assessed as antimalarial agents. The structures of the 1, 2, 4-triazine-quinoline hybrids were …

Malaria is a very destructive and lethal parasitic disease that causes significant mortality
worldwide, resulting in the loss of millions of lives annually. It is an infectious disease …

Antimalarial resistance has hampered the effective treatment of malaria, a parasitic disease
caused by Plasmodium species. As part of our campaign on phenotypic screening of …

A library of six compounds with new hybrids in a single molecule triazole ring attached to the
phosphonium salts was synthesized. Click chemistry was, however, used to synthesize the 1 …

As one of the novel antimalarial targets, the Plasmodium falciparum dihydroorotate
dehydrogenase (PfDHODH), which catalyzed the production of orotic acids, needs to be …

A library of six compounds with new hybrids in a single molecule triazole ring attached to the
phosphonium salts was synthesized. Click chemistry was, however, used to synthesize the 1 …