Among the chaperones and co-chaperones regulating the glucocorticoid receptor (GR),
FK506 binding protein (FKBP) 51 is the most intensely investigated across different …

The immunophilin FK506 binding protein 51 (FKBP51) has emerged as one of the most
intensely investigated proteins in stress-related mental disorders. It was originally …

Posttraumatic stress disorder (PTSD) can develop after exposure to severe psychological
trauma, leaving patients with disabling anxiety, nightmares, and flashbacks. Current …

Early life stress (ELS) adversely affects the brain and is commonly associated with the
etiology of mental health disorders, like depression. In addition to the mood-related …

Background Chronic alcohol exposure can alter glucocorticoid receptor (GR) function in
some brain areas that promotes escalated and compulsive‐like alcohol intake. GR …

Major depression disorder is one of the most common psychiatric diseases. Recent
evidence supports that environmental stress affects gene expression and promotes the …

Introduction Exposure to stress, mediated through the hypothalamic–pituitary–adrenal (HPA)
axis, elicits sex differences in endocrine, neurological, and behavioral responses. However …

Steroid receptors form soluble heterocomplexes with the 90-kDa heat-shock protein (Hsp90)
and other chaperones and co-chaperones. The assembly and composition of the oligomer is …

Stress and inflammation are risk factors for schizophrenia. Chronic psychosocial stress is
associated with subcortical hyperdopaminergia, a core feature of schizophrenia …

Lymphocytes represent the key antigen‐specific leukocyte subpopulation. Despite their
importance in mounting an immune response, an unbiased description of proteins …