The role of epigenetic factors in psoriasis

K Dopytalska, P Ciechanowicz, K Wiszniewski… - International Journal of …, 2021 - mdpi.com
Psoriasis is a chronic, systemic, immune-mediated disease with an incidence of
approximately 2%. The pathogenesis of the disease is complex and not yet fully understood …

MicroRNA-155—at the critical interface of innate and adaptive immunity in arthritis

S Alivernini, E Gremese, C McSharry… - Frontiers in …, 2018 - frontiersin.org
MicroRNAs (miRNAs) are small non-coding RNAs that fine-tune the cell response to a
changing environment by modulating the cell transcriptome. miR-155 is a multifunctional …

Epigenetic mechanisms of epidermal differentiation

C Moltrasio, M Romagnuolo, AV Marzano - International journal of …, 2022 - mdpi.com
Keratinocyte differentiation is an essential process for epidermal stratification and stratum
corneum formation. Keratinocytes proliferate in the basal layer of the epidermis and start …

The role of microRNA in psoriasis: A review

X Jiang, R Shi, R Ma, X Tang, Y Gong… - Experimental …, 2023 - Wiley Online Library
Psoriasis is a chronic immune‐mediated inflammatory skin disease that involves a complex
interplay between infiltrated immune cells and keratinocytes. Great progress has been made …

Deregulation of microRNA expression in purified T and B lymphocytes from patients with primary Sjögren's syndrome

SF Wang-Renault, S Boudaoud, G Nocturne… - Annals of the …, 2018 - ard.bmj.com
Objective MicroRNAs (miRNAs) play an important role in the pathogenesis of autoimmune
diseases such as primary Sjögren's syndrome (pSS). This study is the first to investigate …

A comprehensive review on miR-146a molecular mechanisms in a wide spectrum of immune and non-immune inflammatory diseases

SS Mortazavi-Jahromi, M Aslani, A Mirshafiey - Immunology Letters, 2020 - Elsevier
MicroRNAs (miRNAs) are single-strand endogenous and non-coding RNA molecules with a
length of about 22 nucleotides, which regulate genes expression, through modulating the …

MicroRNAs in several cutaneous autoimmune diseases: Psoriasis, cutaneous lupus erythematosus and atopic dermatitis

S Domingo, C Solé, T Moliné, B Ferrer… - Cells, 2020 - mdpi.com
MicroRNAs (miRNAs) are endogenous small non-coding RNA molecules that regulate the
gene expression at a post-transcriptional level and participate in maintaining the correct cell …

Pathogenesis of psoriasis in the “omic” era. Part II. Genetic, genomic and epigenetic changes in psoriasis

B Nedoszytko, A Szczerkowska-Dobosz… - … in Dermatology and …, 2020 - termedia.pl
Psoriasis is a multifactorial disease in which genetic, environmental and epigenetic factors
regulating gene expression play a key role. In the “genomic era”, genome-wide association …

The essential role of micrornas in inflammatory and autoimmune skin diseases—a review

K Dopytalska, A Czaplicka, E Szymańska… - International Journal of …, 2023 - mdpi.com
The etiopathogenesis of autoimmune skin diseases is complex and still not fully understood.
The role of epigenetic factors is emphasized in the development of such diseases …

Understanding psoriasis: Role of miRNAs

TL Timis, RI Orasan - Biomedical reports, 2018 - spandidos-publications.com
Psoriasis is a chronic, immune-mediated inflammatory skin disease, with a multifactorial
etiology and important immunologic, genetic and environmental components. Psoriasis …