Acromegaly is a chronic systemic disease with many complications and is associated with
increased mortality when not adequately treated. Substantial advances in acromegaly …

The important role of GH in the control of mammalian longevity was first deduced from
extended longevity of mice with genetic GH deficiency (GHD) or GH resistance. Mice with …

Context Acromegaly has been associated with increased risk of cancer morbidity and
mortality, but research findings remain conflicting and population-based data are scarce. We …

Acromegaly is caused by excess growth hormone (GH) secretion emanating from a
somatotroph adenoma. High GH and Insulin-like growth factor-1 (IGF-1) levels lead to acral …

Mortality in acromegaly: a 20-year follow-up study in: Endocrine-Related Cancer Volume 23
Issue 6 (2016) Jump to Content Endocrine-Related Cancer journal logo Endocrine-Related …

Several components of the GH axis are involved in tumor progression, and GH-induced
intracellular signaling has been strongly associated with breast cancer susceptibility in …

Based on experimental and animal models, epidemiological data from non-acromegaly
populations, and longitudinal and cross-sectional cohorts of patients with acromegaly, a …

Purpose Recent data have shown a decreasing overall mortality in acromegaly over the last
decades. However, cancer incidence and cancer-related mortality still appear to be …

Acromegaly is a rare, chronic, progressive disease characterized by an excess secretion of
growth hormone (GH) and increased circulating insulin-like growth factor 1 (IGF-1) …

Androgen-deprivation therapy (ADT) is the standard treatment for metastatic prostate cancer.
One factor that has been implicated in the metastatic process is the cell adhesion molecule …