Subcellular compartmentalization of metabolic pathways plays a crucial role in metabolic
engineering. The peroxisome has emerged as a highly valuable and promising …

Highlights•Enzyme matching/engineering and metabolite channeling enhance microbial
production.•Product sequestration is key to improving the production of lipophilic …

Highlights•Artificial intelligence tools are emerging as valuable gears in synthetic
biology.•Plant-based products and technologies are key solutions for a bio-based …

Squalene is a high-value antioxidant with many commercial applications. The use of
microbial cell factories to produce squalene as an alternative to plant and animal extracts …

Squalene is a highly sought-after triterpene compound in growing demand, and its
production offers a promising avenue for circular economy practices. In this study, we …

Sesquiterpenes and tetraterpenes are classes of plant-derived natural products with
antineoplastic effects. While plant extraction of the sesquiterpene, germacrene A, and the …

Squalеnе is a natural organic compound and tritеrpеnе sourcеd primarily from shark livеr
oil. Squalеnе plays a crucial rolе in thе synthеsis pathway of all stеrols. It is widely used in …

摘要合成生物学通过引入工程科学“自下而上” 认识生命体系的理念, 在生命科学研究中采用“
设计—构建—测试—学习” 迭代的研究范式, 并在基因组和系统生物学的基础上 …

Background Limonene has a variety of applications in the foods, cosmetics,
pharmaceuticals, biomaterials, and biofuels industries. In order to meet the growing demand …

Synthetic biology revolutionizes the comprehension of life systems from an engineering
perspective, employing a “bottomup” approach in life science research. It adopts an iterative …