Within the last two decades, the field of nanomedicine has not developed as successfully as
has widely been hoped for. The main reason for this is the immense complexity of the …

Despite the difficulties associated with controlling the polymerization of ring-strained
nitrogen containing monomers, the resulting polymers have many important applications …

DOI: 10.1002/adma. 201504288 a reactive oxygen species (ROS)-labile charge-reversal
polymer, poly [(2-acryloyl) ethyl (p-boronic acid benzyl) diethylammonium bromide](B …

Therapeutic application of nucleic acids requires their encapsulation in nanosized carriers
that enable safe and efficient intracellular delivery. Before the desired site of action is …

The natural anionic polysaccharide hyaluronic acid (HA) was modified by introducing
reduction-sensitive disulfide bond between the carboxyl groups and the backbone of HA …

In regenerative medicine and bone tissue engineering, various composite materials are
enormously popular, but the final tissue restoration outcome is not always satisfactory. In this …

Hydrogel nanoparticles—also referred to as polymeric nanogels or macromolecular micelles—
are emerging as promising drug carriers for therapeutic applications. These nanostructures …

With the development of nanotechnology, various types of polymer-based drug delivery
systems have been designed for biomedical applications. Polymer-based drug delivery …

Programmed cell death protein-1 (PD-1) is a prominent immune checkpoint receptor
interacting with its ligand, programmed cell death protein ligand-1 (PD-L1, B7-H1). The PD …

Gene therapy holds great promise for the treatment of acquired and inherited diseases. Non-
viral gene delivery systems are gaining recognition as alternatives to viral gene vectors due …