Zinc (Zn) and its alloys have recently been introduced as a new class of biodegradable
metals with potential application in biodegradable vascular stents. Although an in vivo …

Alginates are attractive in tissue regeneration due to their similarity to the extracellular
matrix, biocompatibility, biodegradability, non-antigenicity, and the ability to undergo …

To improve bone regeneration in oral microenvironment, we generated a novel
biodegradable, antibacterial, and osteoconductive electrospun PLGA/PCL membrane as an …

Dense zirconia ceramics are used in bone applications due to their mechanical strength and
biocompatibility, but lack osseointegration. A porous interface in contact with bone tissue …

Numerous studies have shown that surface topography can promote cell–substrate
associations and deeply influence cell fate. The intracellular mechanism or how micro‐or …

Osseointegration of bone implants is a vital part of the recovery process. Numerous studies
have shown that micropatterned geometries can promote cell-substrate associations and …

New generation bone implants with favourable biocompatibility and long-term antibacterial
activity have attracted a great deal of attention due to their bifunctional regulation on …

The work in this thesis provides mulit-scale contributions towards understanding the effects
of trace metals on the pathological mineralization process relating to both the development …

Due to common bone defects arising from trauma, tumors, infection or bone diseases,
techniques to replace, restore, or regenerate bone have become a major clinical challenge …

Initial cell-surface interactions are guided by the material properties of substrate topography.
To examine if these interactions are also modulated by the presence of zinc, we seeded …