Diabetic kidney disease is expected to increase rapidly over the coming decades with rising
prevalence of diabetes worldwide. Current measures of kidney function based on …

Background Diabetic nephropathy (DN) is one of the catastrophic complications of type 2
diabetes mellitus (T2DM). 45% of DN patients progressed to End Stage Renal Disease …

Aim To investigate the associations of serum α-Klotho and β-Klotho levels with type 2
diabetes mellitus (T2DM) progression. Methods We evaluated 106 healthy controls and 261 …

Aim of the present study was to investigate the possible involvement of TNF-α signaling
pathway and T-lymphocyte activation in DN. Eighty-two diabetic patients [39 male, age 69.5 …

Abstract Aims/Introduction We aimed to study the relationships among the copper (Cu)/zinc
(Zn) ratio, inflammatory biomarkers, and the prevalence of diabetic kidney disease (DKD) in …

OBJECTIVE We explored the prognostic value of three circulating candidate biomarkers—
midregional-proadrenomedullin (MR-proADM), soluble tumor necrosis factor receptor 1 …

Context While inflammation has been associated with kidney function in long-standing
diabetes, its possible association in newly diagnosed diabetes is unknown. Objective To …

Diabetic kidney disease (DKD) is a major microvascular complication of both type 1 and type
2 diabetes. DKD is characterised by injury to both glomerular and tubular compartments …

Background Chronic kidney disease (CKD) is an increasingly significant health issue
worldwide. Early stages of CKD can be asymptomatic and disease trajectory difficult to …

Background Higher circulating levels of tumor necrosis factor (TNF) alpha receptors 1
(TNFR1) and 2 (TNFR2) are associated with increased long-term mortality and impaired …