[HTML][HTML] Cellular mechanotransduction in health and diseases: from molecular mechanism to therapeutic targets

X Di, X Gao, L Peng, J Ai, X Jin, S Qi, H Li… - Signal transduction and …, 2023 - nature.com
Cellular mechanotransduction, a critical regulator of numerous biological processes, is the
conversion from mechanical signals to biochemical signals regarding cell activities and …

New insights into balancing wound healing and scarless skin repair

S Zhou, M Xie, J Su, B Cai, J Li… - Journal of Tissue …, 2023 - journals.sagepub.com
Scars caused by skin injuries after burns, wounds, abrasions and operations have serious
physical and psychological effects on patients. In recent years, the research of scar free …

[HTML][HTML] Bioengineering in salivary gland regeneration

M Hajiabbas, C D'Agostino, J Simińska-Stanny… - Journal of biomedical …, 2022 - Springer
Salivary gland (SG) dysfunction impairs the life quality of many patients, such as patients
with radiation therapy for head and neck cancer and patients with Sjögren's syndrome …

[HTML][HTML] Stress-shape misalignment in confluent cell layers

MR Nejad, LJ Ruske, M McCord, J Zhang… - Nature …, 2024 - nature.com
In tissue formation and repair, the epithelium undergoes complex patterns of motion driven
by the active forces produced by each cell. Although the principles governing how the forces …

[HTML][HTML] Quantitative insights in tissue growth and morphogenesis with optogenetics

MS Mim, C Knight, JJ Zartman - Physical Biology, 2023 - iopscience.iop.org
Cells communicate with each other to jointly regulate cellular processes during cellular
differentiation and tissue morphogenesis. This multiscale coordination arises through the …

Develop Tandem Tension Sensor to Gauge Integrin-Transmitted Molecular Forces

G Niraula, A Pyne, X Wang - ACS sensors, 2024 - ACS Publications
DNA-based tension sensors have innovated the imaging and calibration of
mechanosensitive receptor-transmitted molecular forces, such as integrin tensions …

Whole embryo biomechanics with reverberant optical coherence elastography

M Singh, F Zvietcovich, C Zevallos-Delgado… - Optica, 2024 - opg.optica.org
Many morphogenesis processes during embryo development are fundamentally
biomechanical processes, and disruption of these events can lead to debilitating congenital …

[HTML][HTML] Mechanical Signaling in Dental Pulp Stem Cells

J Zhao, W Du, D Guo, S Wang, W Du - Frontiers in Bioscience …, 2023 - imrpress.com
Dental pulp stem cells (DPSCs) are a type of mesenchymal stem cells derived from dental
pulp that serves as an important model for investigating biological regeneration. DPSCs …

Selection of Force Sensors for In Situ Measurement of Neotissue Microenvironments

M Rodriguez Navas, EM Darling - Tissue Engineering Part A, 2024 - liebertpub.com
Mechanical forces are a critical stimulus in both native and engineered tissues. Direct
measurement of these microenvironmental forces has been challenging, particularly for cell …

[HTML][HTML] The Role of Biophysical Factors in Organ Development: Insights from Current Organoid Models

Y Wyle, N Lu, J Hepfer, R Sayal, T Martinez, A Wang - Bioengineering, 2024 - mdpi.com
Biophysical factors play a fundamental role in human embryonic development. Traditional in
vitro models of organogenesis focused on the biochemical environment and did not …