Anti-oxidative, anti-inflammatory and anti-apoptotic effects of flavonols: targeting Nrf2, NF-κB and p53 pathways in neurodegeneration

M Jazvinšćak Jembrek, N Oršolić, L Mandić, A Sadžak… - Antioxidants, 2021 - mdpi.com
Neurodegenerative diseases are one of the leading causes of disability and death
worldwide. Intracellular transduction pathways that end in the activation of specific …

Flavonols in action: Targeting oxidative stress and neuroinflammation in major depressive disorder

M Jazvinšćak Jembrek, N Oršolić, D Karlović… - International journal of …, 2023 - mdpi.com
Major depressive disorder is one of the most common mental illnesses that highly impairs
quality of life. Pharmacological interventions are mainly focused on altered monoamine …

Bupleurum falcatum L. alleviates nociceptive and neuropathic pain: Potential mechanisms of action

D Ahmadimoghaddam, M Zarei, S Mohammadi… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance In Iranian folkloric medicine, Bupleurum falcatum
L.(Chinese Thoroughwax) has been used as a selective analgesic remedy for several …

Intracerebroventricular microinjection of kaempferol on memory retention of passive avoidance learning in rats: involvement of cholinergic mechanism (s)

M Zarei, S Mohammadi, S Jabbari… - International Journal of …, 2019 - Taylor & Francis
Purpose of the study: Kaempferol (KM) is a flavonoid found in plant-derived foods and
medicinal plants. Recently, it is well established that KM plays a protective role to develop …

A review of the chemistry and biological activities of natural colorants, dyes, and pigments: challenges, and opportunities for food, cosmetics, and pharmaceutical …

A Pasdaran, M Zare, A Hamedi… - Chemistry & …, 2023 - Wiley Online Library
Natural pigments are important sources for the screening of bioactive lead compounds. This
article reviewed the chemistry and therapeutic potentials of over 570 colored molecules from …

Effects of intra-dentate gyrus microinjection of myokine irisin on long-term potentiation in male rats

S Mohammadi, S Oryan, A Komaki, A Eidi… - Arquivos de neuro …, 2019 - SciELO Brasil
Induction of long-term potentiation (LTP) increases the storage capacity of synapses in the
hippocampal dentate gyrus (DG). Irisin is a myokine generated from FNDC5 (a gene …

Antinociceptive activity of Cnicus benedictus L. leaf extract: a mechanistic evaluation

D Ahmadimoghaddam, R Sadeghian… - Research in …, 2020 - journals.lww.com
Background and purpose: Cnicus benedictus, a medicinal herb, traditionally had been used
for the treatment of stomachache pain. In this study, the possible efficacy of Cnicus …

The oral administration of Lotus corniculatus L. attenuates acute and chronic pain models in male rats

S Jabbari, ZA Zakaria, D Ahmadimoghaddam… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Lotus corniculatus L.(Fabaceae) traditionally used in
Persian folk medicine to heal peritoneal inflammation and back pain. Aim of the study To …

Effects of Chaerophyllum macropodum Boiss. leaves essential oil in inflammatory and neuropathic pain: uncovering the possible mechanism of action

S Jabbari, DZ Abed, ZA Zakaria, S Mohammadi - Inflammopharmacology, 2023 - Springer
Abstract Background Chaerophyllum macropodum Boiss.(popularly known as “Jafari farangi
kohestani”) is a predominant medicinal plant traditionally utilized in the treatments of …

Effects of Rhus Coriaria essential oil on depression and anxiety in male rats

Y Golshani, S Mohammadi - Feyz Medical Sciences Journal, 2019 - feyz.kaums.ac.ir
Background: Depression and anxiety are among the most important diseases of human
being. The chemical drugs used to treat these diseases have side effects, therefore, the use …