Retention and selectivity of stationary phases for hydrophilic interaction chromatography

Y Guo, S Gaiki - Journal of Chromatography A, 2011 - Elsevier
More and more polar stationary phases have become available for the separation of small
polar compounds in the past decade as hydrophilic interaction chromatography (HILIC) …

Main interactions and influences of the chromatographic parameters in HILIC separations

G Greco, T Letzel - Journal of chromatographic science, 2013 - academic.oup.com
Hydrophilic interaction liquid chromatography (HILIC) is a popular technique for the
separation of polar compounds, which are poorly retained by reversed-phase liquid …

Optimized Analytical Procedures for the Untargeted Metabolomic Profiling of Human Urine and Plasma by Combining Hydrophilic Interaction (HILIC) and Reverse …

K Contrepois, L Jiang, M Snyder - Molecular & Cellular Proteomics, 2015 - ASBMB
Profiling of body fluids is crucial for monitoring and discovering metabolic markers of health
and disease and for providing insights into human physiology. Since human urine and …

Biomimetic sensor for certain catecholamines employing copper (II) complex and silver nanoparticle modified glassy carbon paste electrode

BJ Sanghavi, SM Mobin, P Mathur, GK Lahiri… - Biosensors and …, 2013 - Elsevier
A dimeric Cu (II) complex [Cu (μ2-hep)(hep-H)] 2· 2ClO4 (1) containing bidentate (hep-H= 2-
(2-hydroxyethyl) pyridine) ligand was synthesized and characterized by single crystal X-ray …

Hydrophilic interaction chromatography

MR Gama, RG da Costa Silva, CH Collins… - TrAC Trends in …, 2012 - Elsevier
In the early 1990s, hydrophilic interaction (liquid) chromatography (HILIC) emerged as a
new separation method. HILIC is becoming increasingly popular for the separation of polar …

Chromatographic characterization of hydrophilic interaction liquid chromatography stationary phases: Hydrophilicity, charge effects, structural selectivity, and …

Y Kawachi, T Ikegami, H Takubo, Y Ikegami… - … of chromatography A, 2011 - Elsevier
Fourteen commercially available particle-packed columns and a monolithic column for
hydrophilic interaction liquid chromatography (HILIC) were characterized in terms of the …

Probing the interaction mode in hydrophilic interaction chromatography

NP Dinh, T Jonsson, K Irgum - Journal of Chromatography a, 2011 - Elsevier
This work aims at characterizing interactions between a select set of probes and 22
hydrophilic and polar commercial stationary phases, to develop an understanding of the …

Investigations on the chromatographic behaviour of zwitterionic stationary phases used in hydrophilic interaction chromatography

RI Chirita, C West, S Zubrzycki, AL Finaru… - … of Chromatography a, 2011 - Elsevier
Two commercial stationary phases possessing a sulfobetaine zwitterionic bonded ligand
(ZIC-HILIC and Nucleodur HILIC) were compared under hydrophilic interaction …

[HTML][HTML] Analytical characterization of DNA and RNA oligonucleotides by hydrophilic interaction liquid chromatography-tandem mass spectrometry

M Huang, X Xu, H Qiu, N Li - Journal of Chromatography A, 2021 - Elsevier
Liquid chromatography-mass spectrometry has been widely implemented as a powerful tool
for providing in-depth characterization of nucleic acid therapeutic modalities, such as anti …

Potential of hydrophilic interaction chromatography for the analytical characterization of protein biopharmaceuticals

A Periat, S Fekete, A Cusumano, JL Veuthey… - … of chromatography A, 2016 - Elsevier
A new stationary phase based on wide-pore hybrid silica bonded with amide ligand has
been used to explore the utility of HILIC for the analytical characterization of protein …