SARS-CoV-2-specific immune response and the pathogenesis of COVID-19
E Gusev, A Sarapultsev, L Solomatina… - International journal of …, 2022 - mdpi.com
The review aims to consolidate research findings on the molecular mechanisms and
virulence and pathogenicity characteristics of coronavirus disease (COVID-19) causative …
virulence and pathogenicity characteristics of coronavirus disease (COVID-19) causative …
How can we use the endocytosis pathways to design nanoparticle drug-delivery vehicles to target cancer cells over healthy cells?
VT Cong, JL Houng, M Kavallaris, X Chen… - Chemical Society …, 2022 - pubs.rsc.org
Targeted drug delivery in cancer typically focuses on maximising the endocytosis of drugs
into the diseased cells. However, there has been less focus on exploiting the differences in …
into the diseased cells. However, there has been less focus on exploiting the differences in …
Insight into the role of clathrin‐mediated endocytosis inhibitors in SARS‐CoV‐2 infection
Emergence of SARS‐CoV‐2 variants warrants sustainable efforts to upgrade both the
diagnostic and therapeutic protocols. Understanding the details of cellular and molecular …
diagnostic and therapeutic protocols. Understanding the details of cellular and molecular …
A bipotential organoid model of respiratory epithelium recapitulates high infectivity of SARS-CoV-2 Omicron variant
The airways and alveoli of the human respiratory tract are lined by two distinct types of
epithelium, which are the primary targets of respiratory viruses. We previously established …
epithelium, which are the primary targets of respiratory viruses. We previously established …
Identification of immunomodulatory drugs that inhibit multiple inflammasomes and impair SARS-CoV-2 infection
L de Almeida, ALN da Silva, TS Rodrigues… - Science …, 2022 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces mild or
asymptomatic COVID-19 in most cases, but some patients develop an excessive …
asymptomatic COVID-19 in most cases, but some patients develop an excessive …
CLIC and membrane wound repair pathways enable pandemic norovirus entry and infection
Globally, most cases of gastroenteritis are caused by pandemic GII. 4 human norovirus
(HuNoV) strains with no approved therapies or vaccines available. The cellular pathways …
(HuNoV) strains with no approved therapies or vaccines available. The cellular pathways …
SARS-CoV-2 infection of phagocytic immune cells and COVID-19 pathology: Antibody-dependent as well as independent cell entry
O Matveeva, Y Nechipurenko, D Lagutkin… - Frontiers in …, 2022 - frontiersin.org
Our review summarizes the evidence that COVID-19 can be complicated by SARS-CoV-2
infection of immune cells. This evidence is widespread and accumulating at an increasing …
infection of immune cells. This evidence is widespread and accumulating at an increasing …
SIM imaging resolves endocytosis of SARS-CoV-2 spike RBD in living cells
L Miao, C Yan, Y Chen, W Zhou, X Zhou, Q Qiao… - Cell chemical …, 2023 - cell.com
It is urgent to understand the infection mechanism of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) for the prevention and treatment of COVID-19. The infection of …
coronavirus 2 (SARS-CoV-2) for the prevention and treatment of COVID-19. The infection of …
COVID‐19 metabolism: Mechanisms and therapeutic targets
T Wang, Y Cao, H Zhang, Z Wang, CH Man… - MedComm, 2022 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) dysregulates antiviral
signaling, immune response, and cell metabolism in human body. Viral genome and …
signaling, immune response, and cell metabolism in human body. Viral genome and …
Antiviral and Immunomodulatory Effects of Pelargonium sidoides DC. Root Extract EPs® 7630 in SARS-CoV-2-Infected Human Lung Cells
Treatment options for COVID-19 are currently limited. Drugs reducing both viral loads and
SARS-CoV-2-induced inflammatory responses would be ideal candidates for COVID-19 …
SARS-CoV-2-induced inflammatory responses would be ideal candidates for COVID-19 …