Multiscale biomechanics and mechanotransduction from liver fibrosis to cancer

N Li, X Zhang, J Zhou, W Li, X Shu, Y Wu… - Advanced Drug Delivery …, 2022 - Elsevier
A growing body of multiscale biomechanical studies has been proposed to highlight the
mechanical cues in the development of hepatic fibrosis and cancer. At the cellular level …

Magnetic resonance elastography in the study of neurodegenerative diseases

Y Feng, MC Murphy, E Hojo, F Li… - Journal of Magnetic …, 2024 - Wiley Online Library
Neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease
(PD) present a major health burden to society. Changes in brain structure and cognition are …

[HTML][HTML] Engineered human liver based on pullulan-dextran hydrogel promotes mice survival after liver failure

C Le Guilcher, G Merlen, A Dellaquila, MN Labour… - Materials Today Bio, 2023 - Elsevier
Liver tissue engineering approaches aim to support drug testing, assistance devices, or
transplantation. However, their suitability for clinical application remains unsatisfactory …

Finite element modeling of traumatic brain injury: Areas of future interest

E Griffiths, S Budday - Current Opinion in Biomedical Engineering, 2022 - Elsevier
The use of the finite element (FE) method to simulate traumatic brain injury (TBI) has been
an area under development and research for many years. The aim is to accurately …

COMPRESSIVE RESPONSE OF WHITE MATTER AT LOW STRAIN RATES

L Su, B Qi, J Yin, X Qin, GM Genin, S Liu… - International Journal of …, 2024 - Elsevier
The low strain-rate response of brain parenchyma is critical to predicting prognosis in cases
of hydrocephalus or cerebral edema, including in the prediction of brain stem herniation …

Characterization of elastic modulus and hardness of brittle solids by instrumented indentation

Z Xu, M Liu, J Gong - Acta Mechanica Sinica, 2025 - Springer
The reduced elastic modulus E r and indentation hardness H IT of various brittle solids
including ceramics, semiconductors, glasses, single crystals, and laser material were …

Deep Learning for High Speed Optical Coherence Elastography with a Fiber Scanning Endoscope

M Neidhardt, S Latus, T Eixmann… - … on Medical Imaging, 2024 - ieeexplore.ieee.org
Tissue stiffness is related to soft tissue pathologies and can be assessed through palpation
or via clinical imaging systems, eg, ultrasound or magnetic resonance imaging. Typically …

Needle-induced cavitation: A method to probe the local mechanics of brain tissue

CE Dougan, H Fu, AJ Crosby, SR Peyton - Journal of the Mechanical …, 2024 - Elsevier
Traditional mechanical characterization of extremely soft tissues is challenging given
difficulty extracting tissue, satisfying geometric requirements, keeping tissues hydrated, and …

[HTML][HTML] Macro-indentation testing of soft biological materials and assessment of hyper-elastic material models from inverse finite element analysis

V Ayyalasomayajula, Ø Ervik, H Sorger… - Journal of the Mechanical …, 2024 - Elsevier
Mechanical characterization of hydrogels and ultra-soft tissues is a challenging task both
from an experimental and material parameter estimation perspective because they are much …

Surface wave elastography using high speed full-field optical interferometry

A Singh, P Kumar, S Yeleswarapu… - Biomedical Physics & …, 2022 - iopscience.iop.org
The assessment of mechanical stiffness is an essential diagnostic tool for investigating the
biomechanical properties of biological tissues. Surface wave elastography (SWE) is an …