COVID-19 and cellular senescence
CA Schmitt, T Tchkonia, LJ Niedernhofer… - Nature Reviews …, 2023 - nature.com
The clinical severity of coronavirus disease 2019 (COVID-19) is largely determined by host
factors. Recent advances point to cellular senescence, an ageing-related switch in cellular …
factors. Recent advances point to cellular senescence, an ageing-related switch in cellular …
Interconnections between inflammageing and immunosenescence during ageing
Acute inflammation is a physiological response to injury or infection, with a cascade of steps
that ultimately lead to the recruitment of immune cells to clear invading pathogens and heal …
that ultimately lead to the recruitment of immune cells to clear invading pathogens and heal …
[HTML][HTML] Risk factors and disease profile of post-vaccination SARS-CoV-2 infection in UK users of the COVID Symptom Study app: a prospective, community-based …
Background COVID-19 vaccines show excellent efficacy in clinical trials and effectiveness in
real-world data, but some people still become infected with SARS-CoV-2 after vaccination …
real-world data, but some people still become infected with SARS-CoV-2 after vaccination …
Symptom persistence despite improvement in cardiopulmonary health–insights from longitudinal CMR, CPET and lung function testing post-COVID-19
MP Cassar, EM Tunnicliffe, N Petousi… - …, 2021 - thelancet.com
Background The longitudinal trajectories of cardiopulmonary abnormalities and symptoms
following infection with coronavirus disease (COVID-19) are unclear. We sought to describe …
following infection with coronavirus disease (COVID-19) are unclear. We sought to describe …
Review of COVID-19 mRNA Vaccines: BNT162b2 and mRNA-1273
SP Teo - Journal of pharmacy practice, 2022 - journals.sagepub.com
The United States Food and Drug Administration recently issued emergency use
authorization for 2 mRNA vaccines for preventing COVID-19 disease caused by SARS-CoV …
authorization for 2 mRNA vaccines for preventing COVID-19 disease caused by SARS-CoV …
The role of epithelial damage in the pulmonary immune response
Pulmonary epithelial cells are widely considered to be the first line of defence in the lung
and are responsible for coordinating the innate immune response to injury and subsequent …
and are responsible for coordinating the innate immune response to injury and subsequent …
A systematic review and meta-analysis of the effectiveness and safety of COVID-19 vaccination in older adults
K Xu, Z Wang, M Qin, Y Gao, N Luo, W Xie… - Frontiers in …, 2023 - frontiersin.org
In the coronavirus disease 2019 (COVID-19) pandemic, vaccinations were essential in
preventing COVID-19 infections and related mortality in older adults. The objectives of this …
preventing COVID-19 infections and related mortality in older adults. The objectives of this …
Inter-individual variation in objective measure of reactogenicity following COVID-19 vaccination via smartwatches and fitness bands
The ability to identify who does or does not experience the intended immune response
following vaccination could be of great value in not only managing the global trajectory of …
following vaccination could be of great value in not only managing the global trajectory of …
Impact of vaccination on SARS-CoV-2 cases in the community: a population-based study using the UK's COVID-19 Infection Survey
Objectives To assess the effectiveness of COVID-19 vaccination in preventing SARS-CoV-2
infection in the community. Design Prospective cohort study. Setting The UK population …
infection in the community. Design Prospective cohort study. Setting The UK population …
Regulation of the immune system by the insulin receptor in health and disease
The signaling pathways downstream of the insulin receptor (InsR) are some of the most
evolutionarily conserved pathways that regulate organism longevity and metabolism. InsR …
evolutionarily conserved pathways that regulate organism longevity and metabolism. InsR …