Improving lung health in low-income and middle-income countries: from challenges to solutions

J Meghji, K Mortimer, A Agusti, BW Allwood, I Asher… - The Lancet, 2021 - thelancet.com
Low-income and middle-income countries (LMICs) bear a disproportionately high burden of
the global morbidity and mortality caused by chronic respiratory diseases (CRDs), including …

Subclinical tuberculosis disease—a review and analysis of prevalence surveys to inform definitions, burden, associations, and screening methodology

B Frascella, AS Richards, B Sossen… - Clinical Infectious …, 2021 - academic.oup.com
While it is known that a substantial proportion of individuals with tuberculosis disease (TB)
present subclinically, usually defined as bacteriologically-confirmed but negative on …

Incipient and subclinical tuberculosis: a clinical review of early stages and progression of infection

PK Drain, KL Bajema, D Dowdy, K Dheda… - Clinical microbiology …, 2018 - Am Soc Microbiol
Tuberculosis (TB) is the leading infectious cause of mortality worldwide, due in part to a
limited understanding of its clinical pathogenic spectrum of infection and disease …

Xpert MTB/RIF and Xpert MTB/RIF Ultra for pulmonary tuberculosis and rifampicin resistance in adults

JS Zifodya, I Schiller, N Dendukuri… - Cochrane Database …, 2019 - cochranelibrary.com
Background Xpert MTB/RIF (Xpert MTB/RIF) and Xpert MTB/RIF Ultra (Xpert Ultra), the
newest version, are the only World Health Organization (WHO)‐recommended rapid tests …

New developments in tuberculosis diagnosis and treatment

CM Gill, L Dolan, LM Piggott, AM McLaughlin - Breathe, 2022 - Eur Respiratory Soc
Tuberculosis (TB) is a major cause of morbidity and mortality worldwide. It is estimated that
25% of the world's population are infected with Mycobacterium tuberculosis, with a 5–10 …

Tuberculosis: advances and challenges in development of new diagnostics and biomarkers

G Walzl, R McNerney, N du Plessis, M Bates… - The Lancet Infectious …, 2018 - thelancet.com
Tuberculosis remains the leading cause of death from an infectious disease worldwide.
Early and accurate diagnosis and detection of drug-sensitive and drug-resistant tuberculosis …

[HTML][HTML] Emergence of a novel coronavirus causing respiratory illness from Wuhan, China

JW Tang, PA Tambyah, DSC Hui - The Journal of infection, 2020 - ncbi.nlm.nih.gov
In previous reports, workers have characterized the presentation of Middle East Respiratory
Syndrome (MERS) 1 and Severe Acute Respiratory Syndrome (SARS) 2 to aid clinical …

Xpert® MTB/RIF assay for extrapulmonary tuberculosis and rifampicin resistance

M Kohli, I Schiller, N Dendukuri… - Cochrane Database …, 2018 - cochranelibrary.com
Background Tuberculosis (TB) is the world's leading infectious cause of death.
Extrapulmonary TB accounts for 15% of TB cases, but the proportion is increasing, and over …

Xpert MTB/RIF Ultra assay for tuberculosis disease and rifampicin resistance in children

AW Kay, T Ness, SE Verkuijl, K Viney… - Cochrane Database …, 2022 - cochranelibrary.com
Background Every year, an estimated one million children and young adolescents become
ill with tuberculosis, and around 226,000 of those children die. Xpert MTB/RIF Ultra (Xpert …

The epidemiological importance of subclinical tuberculosis. A critical reappraisal

EA Kendall, S Shrestha, DW Dowdy - American journal of …, 2021 - atsjournals.org
From Chlamydia (1) to malaria (2) to severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2)(3), it is increasingly recognized that individuals without recognizable …