Oxidative stress in bone remodelling and disease

F Wauquier, L Leotoing, V Coxam, J Guicheux… - Trends in molecular …, 2009 - cell.com
Oxidative stress is characterised by an increased level of reactive oxygen species (ROS)
that disrupts the intracellular reduction–oxidation (redox) balance. Although initially shown …

Ferroptosis in inflammatory arthritis: a promising future

S Chang, M Tang, B Zhang, D Xiang, F Li - Frontiers in Immunology, 2022 - frontiersin.org
Ferroptosis is a kind of regulatory cell death (RCD) caused by iron accumulation and lipid
peroxidation, which is characterized by mitochondrial morphological changes and has a …

Oxidative stress-mediated mitochondrial dysfunction facilitates mesenchymal stem cell senescence in ankylosing spondylitis

G Ye, Z Xie, H Zeng, P Wang, J Li, G Zheng… - Cell Death & …, 2020 - nature.com
Ankylosing spondylitis (AS) is a chronic inflammatory disease possessing a morbid serum
microenvironment with enhanced oxidative stress. Long-term exposure to an oxidative …

Oxidative stress in patients with rheumatoid arthritis

A García-González, R Gaxiola-Robles… - Revista de …, 2015 - medigraphic.com
Background: Rheumatoid arthritis is an autoimmune disease of unknown etiology,
characterized by articular inflammation. Oxidative damage induced by reactive oxygen …

A dietary colorant crocin mitigates arthritis and associated secondary complications by modulating cartilage deteriorating enzymes, inflammatory mediators and …

M Hemshekhar, MS Santhosh, K Sunitha… - Biochimie, 2012 - Elsevier
Articular cartilage degeneration and inflammation are the hallmark of progressive arthritis
and is the leading cause of disability in 10–15% of middle aged individuals across the world …

Role of flavonoids on oxidative stress and mineral contents in the retinoic acid-induced bone loss model of rat

N Oršolić, E Goluža, D Đikić, D Lisičić, K Sašilo… - European journal of …, 2014 - Springer
Purpose Reactive oxygen species play a role in a number of degenerative conditions
including osteoporosis. Flavonoids as phyto-oestrogens exert physiological effects against …

Immunological and oxidative stress biomarkers in Ankylosing Spondylitis patients with or without metabolic syndrome

A Pishgahi, R Abolhasan, S Danaii, B Amanifar… - Cytokine, 2020 - Elsevier
Ankylosing Spondylitis (AS) is a chronic inflammatory disorder of the spine and sacroiliac
joints with unidentified etiology closely associated with metabolic syndrome (MetS). Recent …

[HTML][HTML] Environmental and genetic determinants of ankylosing spondylitis

R Bilski, P Kamiński, D Kupczyk, S Jeka… - International Journal of …, 2024 - mdpi.com
Exposure to heavy metals and lifestyle factors like smoking contribute to the production of
free oxygen radicals. This fact, combined with a lowered total antioxidant status, can induce …

No evidence of a genetic causal relationship between ankylosing spondylitis and iron homeostasis: a two-sample Mendelian randomization study

M Yang, H Yu, K Xu, J Xie, H Zheng, R Feng… - Frontiers in …, 2023 - frontiersin.org
Background Ankylosing spondylitis (AS) is an immune-mediated chronic inflammatory
disease that leads to bone hyperplasia and spinal ankylosis. Iron homeostasis plays a very …

Emerging Landscape of Mesenchymal Stem Cell Senescence Mechanisms and Implications on Therapeutic Strategies

J Wang, M Zhang, H Wang - ACS Pharmacology & Translational …, 2024 - ACS Publications
Mesenchymal stem cells (MSCs) hold significant promise for regenerative medicine and
tissue engineering due to their unique multipotent differentiation ability and …