Iodine has been found to be an effective Lewis acid for promoting the per-O-acetylation of
unprotected sugars. Under controlled conditions it can bring about regioselective acylation …

The original synthesis of combretastatin A-1 (1) was modified to allow an efficient scale-up
procedure for obtaining this antineoplastic stilbene. Subsequent conversion to a useful …

The oxidative debenzylation of N-benzyl amides and O-benzyl ethers was promoted with
high efficiency by a bromo radical formed through the oxidation of bromide from alkali metal …

Benzyl ether and benzylidene acetal carbohydrate protecting groups can be selectively
cleaved by reaction with sodium bromate/sodium dithionite in ethyl acetate/water. Under the …

Iron (III) halides have proven to be excellent catalysts in the coupling of acetylenes and
aldehydes. When terminal acetylenes were used the main products obtained were 1, 5 …

Anhydrous FeCl3 in CH2Cl2 at room temperature and 0° C has been used to debenzylate
monosaccharides and oligosaccharides in yields generally greater than 70%. Notably …

Tetrahedron Letters,Vo1.28,No.33,pp 3823-3824,1987 oo40-4039/87 $3.00 + .OO Printed in
Great Britain Pergamon Journals Ltd. 3823 Page 1 Tetrahedron Letters,Vo1.28,No.33,pp …

The reaction between per-O-acetylated hexopyranoses and suitable thiols in the presence
of anhydrous ferric chloride affords the corresponding thioglycosides. Thus, ethyl 1-thio-ß-D …

TCP-and phthalimide-protected n-pentenyl glucosaminide (NPG) precursors have been
utilized in a convergent stereocontrolled synthesis of the nodulation factor NodRf-III (C18: 1 …

4-Methoxyphenylmethyl ethers are widely utilized as alcohol protecting groups. FeCl3
effectively catalyzes the deprotection of methoxyphenylmethyl-type ethers in a self-cleaving …