Microglia are emerging as critical regulators of neuronal function and behavior in nearly
every area of neuroscience. Initial reports focused on classical immune functions of …

Advances in cancer treatments mean that half of people now diagnosed with cancer can
expect to survive for at least 10 years, 1 defining many cancers as long term conditions …

Major depressive disorder (MDD), which is a leading psychiatric illness across the world,
severely affects quality of life and causes an increased incidence of suicide. Evidence from …

Cytokines have been implicated in the pathology of depression. Currently, the evidence is
based on cross-sectional studies and meta-analytic research comparing blood …

Cancer is a life-altering event causing considerable psychological distress. However,
information on the total burden of psychiatric disorders across all common adult cancers and …

Context Symptom researchers have proposed a model of inflammatory cytokine activity and
dysregulation in cancer to explain co-occurring symptoms including pain, fatigue, and sleep …

Depression is a common comorbidity in cancer cases, but this is not only due to the
emotional distress of having a life-threatening disease. A common biological mechanism …

Cancer cachexia is a multifactorial syndrome that is characterised by a loss of skeletal
muscle mass, is commonly associated with adipose tissue wasting and malaise, and …

Background Systemic inflammation is associated with reduced quality of life and increased
symptoms in patients with advanced cancer. The aims of this study were to examine the …

Little is known about quality of life (QOL) of patients with pancreatic cancer and their
caregivers compared with adults with other cancers. This systematic review summarizes the …