Schwann cells within the peripheral nervous system possess a remarkable regenerative
potential. Current research shows that peripheral nerve‐associated Schwann cells possess …

Peripheral nerve repair and regeneration remains among the greatest challenges in tissue
engineering and regenerative medicine. Even though peripheral nerve injuries (PNIs) are …

Peripheral nerve injury is a complex condition with a variety of signs and symptoms such as
numbness, tingling, jabbing, throbbing, burning or sharp pain. Peripheral nerves are fragile …

Mechanistic understanding of the topological cues delivered by biomaterials in promotion of
oriented tissue regeneration (eg., peripheral nerve regrowth) remains largely elusive. Here …

Tissue engineering (TE) holds an enormous potential to develop functional scaffolds
resembling the structural organization of native tissues, to improve or replace biological …

Silk fibroin has become a promising biomaterial owing to its remarkable mechanical
property, biocompatibility, biodegradability, and sufficient supply. However, it is difficult to …

Tissue engineered nerve grafts (TENGs) have emerged as a potential alternative to
autologous nerve grafts, the gold standard for peripheral nerve repair. Typically, TENGs are …

Abstract Myelination of Schwann cells (SCs) is critical for the success of peripheral nerve
regeneration, and biomaterials that can promote SCs' neurotrophin secretion as scaffolds …

Microsurgical techniques for the treatment of large peripheral nerve injuries (such as the
gold standard autograft) and its main clinically approved alternative—hollow nerve guidance …

Peripheral nerve injury is a worldwide clinical problem which could lead to loss of neuronal
communication along sensory and motor nerves between the central nervous system (CNS) …