Organoselenium and organotellurium compounds: toxicology and pharmacology

CW Nogueira, G Zeni, JBT Rocha - Chemical reviews, 2004 - ACS Publications
Organoselenium compounds have found such wide utility because of their effects on an
extraordinary number of very different reactions, including many carbon-carbon bond …

Toxicology and pharmacology of selenium: emphasis on synthetic organoselenium compounds

CW Nogueira, JBT Rocha - Archives of Toxicology, 2011 - Springer
The advance in the area of synthesis and reactivity of organoselenium, as well as the
discovery that selenium was the cause of severe intoxication episodes of livestock in the …

[HTML][HTML] Diphenyl diselenide a janus-faced molecule

CW Nogueira, JBT Rocha - Journal of the Brazilian Chemical Society, 2010 - SciELO Brasil
In this review, we summarized the potential role of synthetic organoseleno compounds as
therapeutic or toxic agents, giving emphasis almost exclusively to diphenyl diselenide, the …

Phenolic content and antioxidant property of the bark extracts of Ziziphus mucronata Willd. subsp. mucronata Willd

OO Olajuyigbe, AJ Afolayan - BMC Complementary and Alternative …, 2011 - Springer
Background Several plants traditionally used in treatment of a variety of infections in South
Africa are reported in ethnobotanical surveys. Many of these plants including Ziziphus …

Antioxidant effect of alkynylselenoalcohol compounds on liver and brain of rats in vitro

CI Acker, R Brandão, AR Rosário… - Environmental Toxicology …, 2009 - Elsevier
Alkynylselenoalcohol compounds were screened for in vitro antioxidant activity.
Alkynylselenoalcohols (2a–2d) were tested against lipid and protein oxidation induced by …

Organodiselenides: Organic catalysis and drug design learning from glutathione peroxidase

MD Tiezza, G Ribaudo, L Orian - Current Organic Chemistry, 2019 - ingentaconnect.com
Organodiselenides are an important class of compounds characterized by the presence of
two adjacent covalently bonded selenium nuclei. Among them, diaryldiselenides and their …

[HTML][HTML] Protective effect of diphenyl diselenide against peroxynitrite-mediated endothelial cell death: a comparison with ebselen

AF de Bem, B Fiuza, P Calcerrada, PM Brito, G Peluffo… - Nitric oxide, 2013 - Elsevier
Excess production of superoxide (O2−) and nitric oxide (NO) in blood vessel walls may
occur early in atherogenesis leading to the formation of peroxynitrite, a strong oxidant and …

Seleno-indoles trigger reactive oxygen species and mitochondrial dysfunction in Leishmania amazonensis

PC Santana Filho, MB da Silva, BNM da Silva, T Fazolo… - Tetrahedron, 2023 - Elsevier
Leishmaniasis is an endemic disease caused by obligate intracellular protozoa of the genus
Leishmania prevalent in the Americas, Africa, and Asia. Therapeutic options are limited for …

Mitochondrial dysfunction induced by different organochalchogens is mediated by thiol oxidation and is not dependent of the classical mitochondrial permeability …

RL Puntel, DH Roos, V Folmer… - Toxicological …, 2010 - academic.oup.com
Ebselen (Ebs) and diphenyl diselenide [(PhSe) 2] readily oxidize thiol groups. Here we
studied mitochondrial swelling changes in mitochondrial potential (Δψm), NAD (P) H …

Comprehensive Overview of the Effects of Amaranthus and Abelmoschus esculentus on Markers of Oxidative Stress in Diabetes Mellitus

WN Phoswa, K Mokgalaboni - Life, 2023 - mdpi.com
The use of medicinal plants in the management of diabetes mellitus (DM) is extensively
reported. However, there is still very limited information on the role of these plants as …